Details About Generic Salt ::  Eletriptan 

Main Medicine Class:: #N/A   Sub Medicine Class ::  #N/A

1H. ANTI-MIGRAINE & ANTI- VERTIGO DRUGS in 1. NERVOUS SYSTEM
ELETRIPTAN
5-HT1 RECEPTOR AGONIST | ANTI-MIGRAINE
PK: A: Rapid & well absorbed D: Vd: 138 L M: Hepatic

Indications & Dose: MIGRAINE Acute PO Adult Initially 20-40mg, max 40mg, if headache improves but returns, dose may be repeated after 2 hrs have elapsed since first dose, max 80mg/dayIf initial dose is ineffective, re-evaluate diagnosis

Contra: Hypersensitivity to drug, Basilar and hemiplegic migraine, Severe hepatic disease, Ischemic heart disease, Peripheral vascular disease, Cerebrovascular syndromes, Uncontrolled hypertension, Ischemic bowel disease, use Within 24 hours of another 5HT1 agonist/ergot derivatives

Precautions: hepatic or renal impairment, DM, hypercholesterolemia, cardiac disorders

ADR: Serious: asthenia, paresthesia, cerebrovascular ischemia, chest pain, palpitations, hypertension, cardiovascular ischemia, muscle weakness, chest tightness/pressure, flushing, Others: dizziness, insomnia, drowsiness, headache, fatigue, anxiety, nausea, vomiting, diarrhea, dry mouth, hot or cold sensation

DDI: Others Nelfinavir/Indinavir/Ritonavir/Verapamil increases eletriptan levels, Fluconazole/Erythromycin/Ketoconazole raises eletriptan levels, St John’s wort preparations Serotonin syndrome

Monitor: vital signs and assess for chest pain, tightness/pressure

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