Article Contents ::
Details About Generic Salt :: Eszopiclone
Main Medicine Class:: Nervous System Sub Medicine Class :: Sedatives , Hypnotics
| 1A. SEDATIVES & HYPNOTICS in 1. NERVOUS SYSTEM |
| ESZOPICLONE |
| GABA ENHANCER | SEDATIVE, HYPNOTIC |
| PK: A: Rapid M: Hepatic E: Urine (75% as metabolites; <10% as parent drug) |
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Indications & Dose: INSOMNIA Short-term therapy PO Adult 2mg HS, max 3mg Elderly 1mg HS, max 2mg |
| Precautions: Complex sleep-related behaviors, sensitivity reactions, abuse, comorbidities
ADR: Serious: Allergic reactions, xerostomia, anaphylaxis, asthma, dysmenorrhea, Others: nervousness, pruritus, libido, dyspepsia, diarrhea, dizziness, UTI, alopecia DDI: Serious Rifampicin decreases drug level, Itraconazole/Clarithromycin/Ketoconazole/Nelfinavir/Ritonavir increases drug level, AntiConvulsants results in additive effect Diet: Avoid after heavy meal Monitor: Prior to therapy evaluate physical/psychiatric causes of insomnia |