Article Contents ::
Details About Generic Salt :: Ethionamide
Main Medicine Class:: Anti Infectives Sub Medicine Class :: Drugs for Tuberculosis
| 13O. DRUGS FOR TUBERCULOSIS in 13. ANTI-INFECTIVES |
| ETHIONAMIDE |
| THIOAMIDE DERIVATIVE | ANTI-TB & ANTI-LEPROSY |
| also comes under 13P. Anti-Leprotics in 13. Anti-Infectives |
| PK: A: Rapid D: Extensively M: Hepatic E: Urine |
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Indications & Dose: LEPROSY PO Adult 15-20mg/kg/day, max 1g/day Child 15-20mg/kg/day, max 1g/day in 2-3 divided doses | TUBERCULOSIS PO Adult 15-20mg/kg/day, max 1g/day Child 15-20mg/kg/day, max 1g/day in 2-3 divided doses |
| Contra: Hypersensitivity
Precautions: Renal/hepatic impairment, history of psychiatric illness, DM, porphyria ADR: Serious: hepatitis, thrombocytopenia, hypoglycemia, hypothyroidism, postural hypotension, Others: diarrhea, nausea, vomiting, stomatitis, abdominal pain, alopecia, dermatitis, anxiety, depression, dizziness, drowsiness DDI: Serious Cycloserine leads to neurotoxic adverse effects, Isoniazid results in acute psychotic reactions |
