Article Contents ::
Details About Generic Salt :: Famciclovir
| 13M. ANTI-VIRALS (NON RETROVIRAL) in 13. ANTI-INFECTIVES |
| FAMCICLOVIR |
| SYNTHETIC NUCLEOSIDE | ANTI-VIRAL |
| PK: A: Rapid D: 0.91-1.25 L/kg (Vd) M: Hepatic E: Urine (73%), feces (27%) |
|
Indications & Dose: GENITAL HERPES SIMPLEX VIRUS INFECTION PO Adult Initial episode: 250mg TID 7-10 days (immunocompetent) | PO Adult 500mg BID 7 days or 5-10 days (HIV patients) | HERPES ZOSTER Acute PO Adult 500mg q8h 7 days | RECURRENT GENITAL HERPES SIMPLEX VIRUS INFECTION PO Adult 1g BID 1 day (immunocompetent) | RECURRENT HERPES LABIALIS PO Adult 1.5gm single dose initiate at first sign or symptom appear | SUPPRESSION OF RECURRENT EPISODES OF GENITAL HSV INFECT PO Adult 250mg BID up to 1 yr (immunocompetent) |
| Contra: Hypersensitivity
Precautions: Renal impairment ADR: Serious: ARF, jaundice, increased transaminases, bilirubin, Others: headache, nausea, vomiting, dizziness, skin rash, pruritus, urticaria, somnolence, confusion, hallucinations, abdominal pain, fever DDI: Serious Raloxifene inhibits drug metabolism, Probenecid reduces drug renal excretion & increases its levels Diet: With/without food Monitor: CBC |
