Article Contents ::
Details About Generic Salt :: Flunarizine
Main Medicine Class:: Nervous System Sub Medicine Class :: Anti Migraine , Anti Vertigo Drugs
| 1H. ANTI-MIGRAINE & ANTI- VERTIGO DRUGS in 1. NERVOUS SYSTEM |
| FLUNARIZINE |
| H1-RECEPTOR BLOCKER & CCB | ANTI-MIGRAINE |
| PK: A: Well absorbed D: 43.2L/kg (Vd) M: Hepatic E: Urine |
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Indications & Dose: MIGRAINE Prophylactic therapy PO Adult 5-10mg/day HS | PERIPHERAL & CEREBRAL VASCULAR DISORDERS PO Adult 5-10mg/day HS | VERTIGO PO Adult 5-10mg/day HS | VESTIBULAR DISORDERS PO Adult 5-10mg/day HS |
| Contra: Hypersensitivity, depression, parkinson’s disease, extrapyramidal disorders, porphyria
Precautions: Elderly, fatigue, driving/operating machinery, angle-closure glaucoma, urinary retention, prostatic hyperplasia, pyloroduodenal obstruction, epilepsy, severe hepatic impairment ADR: Serious: increased prolactin level, Others: increased appetite, nausea, vomiting, xerostomia, weight gain, heart burn, Anxiety, dizziness, drowsiness, fatigue, insomnia, rash, galactorrhea DDI: Serious Phenytoin/Carbamazepine/Valproic acid reduces drug level Monitor: EPS, fatigue |
