The Brand Name GEMFOS Has Generic Salt :: RISEDRONATE 

GEMFOS  Is From Company ALKEM Priced :: Rs. 120

GEMFOS have RISEDRONATE is comes under Sub class #N/A of  Main Class #N/A

Main Medicine Class:: #N/A  Sub Medicine Class :: #N/A 

Indications for Drugs ::

Paget’s disease of bone, postmenopausal or corticosteroid-induced osteoporosis, increase bone mass in men with osteoporosis

Drug Dose ::

Adult: PO Paget’s disease of bone 30 mg once daily for 2 mth, repeat if needed after 2 mth interval. Treatment or prevention of postmenopausal or corticosteroid-induced osteoporosis 5 mg/day. For postmenopausal osteoporosis, 35 mg once wkly may be given. Increase bone mass in men w/ osteoporosis 35 mg once wkly. Increase bone mass in men with osteoporosis Adult: 35 mg once wkly. Renal impairment: CrCl (ml/min) <30 Avoid use. Contraindication ::

Acute upper GI inflammation, pregnancy, hypocalcaemia and CrCl <30 ml/min. Drug Precautions ::

Correct hypocalcaemia prior to therapy. Monitor hepatic and renal function and WBC. Renal impairment; inability to remain in an upright position for at least 30 min after oral intake.

Drug Side Effects ::

Electrolyte disturbances; GI disturbances; musculoskeletal pain; headache; hypersensitivity reactions; blood disorders; liver enzyme disturbances. Bone, joint and/or muscle pain.

Pregnancy category ::

3

Drug Mode of Action ::  

Risedronic acid inhibits bone resorption by inhibiting osteoclasts. It also prevents formation and dissolution of hydroxyapatite crystals, and therefore may interfere with bone mineralisation.

Drug Interactions ::

Co-admin with calcium, antacids or oral medications containing divalent cations may affect the absorption of risedronate. May have additive calcium lowering effects when used with aminoglycosides.