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Details About Generic Salt :: Glibenclamide , Metformin
Main Medicine Class:: #N/A Sub Medicine Class :: #N/A
8D. INSULIN & ANTI-DIABETIC DRUGS in 8. ENDOCRINE/STEROID HORMONES & METABOLIC SYSTEM |
GLIBENCLAMIDE + METFORMIN |
SULFONYLUREA & BIGUANIDE | ANTI-DIABETIC |
Indications & Dose: TYPE 2 DIABETES MELLITUS Chronic PO Adult Initially glibenclamide 1.25mg/metformin 250mg OD, if the FBS levels >200mg/dL then glibenclamide 1.25mg/metformin 250mg BID. Dose may be increased by 1.25mg/250mg BID max 10mg/2g ODNo prior treatment with sulfonylurea/metformin | Chronic PO Adult Uncontrolled with monotherapy: Initially glibenclamide 2.5mg/metformin 500mg or 5mg/500mg BID max glibenclamide 20mg/ metformin 2g/day |
Contra: renal disease, severe hepatic impairment |