Article Contents ::
- 1 The Brand Name HYTHALTON Has Generic Salt :: Chlorthalidone
- 2 HYTHALTON Is From Company Nicholas Priced :: Rs. 23.8
- 3 HYTHALTON have Chlorthalidone is comes under Sub class Diuretics of Main Class Genito Urinary System
- 4 Main Medicine Class:: Genito Urinary System Sub Medicine Class :: Diuretics
- 5 Disclaimer ::
- 6 The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.
The Brand Name HYTHALTON Has Generic Salt :: Chlorthalidone
HYTHALTON Is From Company Nicholas Priced :: Rs. 23.8
HYTHALTON have Chlorthalidone is comes under Sub class Diuretics of Main Class Genito Urinary System
Main Medicine Class:: Genito Urinary System Sub Medicine Class :: Diuretics
| Salt Name : OR Generic Name | Form | Price : MRP /Probable | Packing | ||
| Chlorthalidone | TAB | Rs. 23.8 | 10 |
| Brand Name | Company / Manufacturers | Strength | Unit | Price / 10 |
| HYTHALTON | Nicholas | 100MG | 10 | Rs. 23.8 |
| Company Brand Name | Salt Combination | Main Medical Class | Sub Medical Class |
| From Nicholas :: HYTHALTON | Chlorthalidone | Genito Urinary System | Diuretics |
Indications for Drugs ::
Hypertension, Oedema, Diabetes insipidus, Congestive heart failure
Drug Dose ::
Adult: PO HTN 25 mg/day, up to 50 mg/day. Oedema Initial: 25-50 mg/day up to 100-200 mg/day in severe cases. Maintenance: 25-50 mg/day or on alternate days. Diabetes insipidus Initial: 100 mg twice daily. Maintenance: 50 mg/day.
Contraindication ::
Severe renal impairment or anuria. Severe hepatic impairment, addison’s disease, preexisting hypercalcaemia, asthma; hypersensitivity; severe allergy. Pregnancy and lactation.
Drug Precautions ::
Existing fluid and electrolyte disturbances, hepatic cirrhosis, severe heart failure, hyperuricaemia, mild to moderate renal impairment. Elderly. Monitor fluid and electrolyte balance. Kidney or liver disease; diabetes; gout; hyperlipidaemia and ventricular extra systoles.
Drug Side Effects ::
Dry mouth, thirst, weakness, lethargy, drowsiness, restlessness, seizures, oliguria, hypotension, fatigue, muscle cramps and GI disturbances, nausea, vomiting, constipation, diarrhoea, anorexia. Diabetes and gout may be precipitated. Impotence. Raised blood levels of glucose, urates, lipids and calcium. Reduced levels of K and magnesium. Raised CPK levels. Potentially Fatal: Rare. Severe hyponatraemia and idiosyncratic hypersensitivity.
Pregnancy category ::
4
Drug Mode of Action ::
Chlortalidone is an oral, long acting antihypertensive/diuretic. It is a monosulfamyl diuretic that acts by enhancing the excretion of sodium and chloride ions, and water by interfering with the transport of sodium ions across the renal tubular epithelium. Their primary site of action appears to be at the cortical diluting segment in the nephron of the loop of Henle.
Drug Interactions ::
NSAIDs antagonise hypotensive action. Suppresses action of oral anticoagulants due to reduced prothrombin activity. Increased risk of hypokalaemia when corticosteroids are given concurrently. Potentially Fatal: Potentiates bone marrow suppression caused by anticancer drugs. Diuretic-induced vol depletion can potentiate aminoglycoside nephrotoxicity. Impairs action of oral hypoglycaemic agents. Enhances digitalis toxicity due to hypokalaemia. vol depletion enhances lithium toxicity, conversely, sudden withdrawal of diuretics may result in subtherapeutic levels of circulating lithium. Prolonged paralysis with tubocurarine due to hypokalaemia.
