Article Contents ::
- 1 The Brand Name KENALFIN Has Generic Salt :: Ketorolac
- 2 KENALFIN Is From Company Gufic Bio. Priced :: Rs. 9.27
- 3 KENALFIN have Ketorolac is comes under Sub class Analgesics , Anti inflammatory Drugs of Main Class Musculoskeletal Disorders , Pain
- 4 Main Medicine Class:: Musculoskeletal Disorders , Pain Sub Medicine Class :: Analgesics , Anti inflammatory Drugs
- 5 Disclaimer ::
The Brand Name KENALFIN Has Generic Salt :: Ketorolac
KENALFIN Is From Company Gufic Bio. Priced :: Rs. 9.27
KENALFIN have Ketorolac is comes under Sub class Analgesics , Anti inflammatory Drugs of Main Class Musculoskeletal Disorders , Pain
Main Medicine Class:: Musculoskeletal Disorders , Pain Sub Medicine Class :: Analgesics , Anti inflammatory Drugs
|Salt Name : OR Generic Name||Form||Price : MRP /Probable||Packing|
Indications for Drugs ::
Moderate to severe pain
Drug Dose ::
Oral Moderate to severe pain Adult: 10 mg every 4-6 hr. Max: 40 mg/day. Max duration: 7 days. Elderly: 10 mg every 6-8 hr. Max duration: 7 days. Parenteral Moderate to severe pain Adult: 60 mg as a single dose via IM inj or 30 mg as a single IV dose. Alternatively, 30 mg every 6 hr via IM or IV admin up to a max of 120 mg daily. Halve the doses in patients weighing <50 kg. Max duration: 2 days; patient should be transferred to oral therapy as soon as possible. Elderly: 30 mg as a single dose via IM inj or 15 mg as a single IV dose. Alternatively, 15 mg every 6 hr via IM or IV admin up to a max of 60 mg daily. Pediatric Patients (2 to 16 years of age): IM Dosing: One dose of 1 mg/kg up to a maximum of 30 mg. IV Dosing: One dose of 0.5 mg/kg up to a maximum of 15 mg. Contraindication ::
Hypersensitivity to aspirin or other NSAIDs, asthma. Hypovolaemia or dehydration. Do not give postoperatively to patients with high risk of haemorrhage. History of peptic ulcer or coagulation disorders. Nasal polyps, angioedema, bronchospasm. Labour. Moderate to severe renal impairment. GI bleeding, cerebrovascular bleeding. As prophylactic analgesic before surgery. Pregnancy, lactation.
Drug Precautions ::
Elderly, patients weighing <50 kg, hepatic dysfunction, heart failure, predisposition to reduced blood volume or renal blood flow. Mild renal impairment; monitor renal function closely. Drug Side Effects ::
GI ulcer, bleeding and perforation, drowsiness, rash, bronchospasm, hypotension, psychosis, dry mouth, fever, bradycardia, chest pain, dizziness, headache, sweating, oedema, pallor, liver function changes. Transient stinging and local irritation (ophthalmic). Potentially Fatal: Anaphylaxis. Severe skin reactions. MI, stroke, GI bleeding.
Pregnancy category ::
Drug Mode of Action ::
Ketorolac inhibits prostaglandin synthesis by decreasing the activity of the cyclooxygenase enzyme.
Drug Interactions ::
May reduce effects of antihypertensives eg ACE inhibitors or angiotensin II receptor antagonists (AIIA). Increased risk of renal toxicity with ACE inhibitors, diuretics. Increased adverse effects with aspirin or other NSAIDs. Hallucinations may occur when used with fluoxetine, thiothixene, alprazolam. Potentially Fatal: Increased risk of GI bleeding with warfarin. May increase toxicity of methotrexate (MTX) and lithium. Increased plasma concentrations with probenecid.