Article Contents ::
- 1 The Brand Name KLOX-D Has Generic Salt :: DICLOXACILLIN
- 2 KLOX-D Is From Company HETERO HC. Priced :: Rs. 49
- 3 KLOX-D have DICLOXACILLIN is comes under Sub class #N/A of Main Class #N/A
- 4 Main Medicine Class:: #N/A Sub Medicine Class :: #N/A
- 5 Disclaimer ::
The Brand Name KLOX-D Has Generic Salt :: DICLOXACILLIN
KLOX-D Is From Company HETERO HC. Priced :: Rs. 49
KLOX-D have DICLOXACILLIN is comes under Sub class #N/A of Main Class #N/A
Main Medicine Class:: #N/A Sub Medicine Class :: #N/A
|Salt Name : OR Generic Name||Form||Price : MRP /Probable||Packing|
Indications for Drugs ::
Pneumonia, Endocarditis, Impetigo, Cellulitis, Septic Arthritis, Surgical Prophylaxis, Otitis externa, Staphylococcal skin infections, Folliculitis, Boils, Carbuncles, Mastitis, Osteomyelitis, Throat infections, Streptococcus Septicaemia
Drug Dose ::
Adult: PO 125-250 mg 6 hrly, may double dose in severe infections. Child: 12.5-25 mg/kg/day in 4 divided doses.
Hypersensitivity to penicillins.
Drug Precautions ::
Very high doses in poor renal function (risk of neurotoxicity) or heart failure. Skin sensitization may occur on direct contact. Monitor serum K concentration, renal and hematological status. Spirochete infections particularly syphilis; suprainfection with penicillin-resistant organisms with prolonged use; avoid intrathecal route; elderly; porphyria.
Drug Side Effects ::
Hypersensitivity reactions including uticaria; fever; joint pains; rashes; angioedema; serum sickness-like reactions; hemolytic anemia; interstitial nephritis; neutropenia; thrombocytopenia; CNS toxicity including convulsions; diarrhea; antibiotic-associated colitis; hepatitis, cholestatic jaundice; agranulocytosis. Potentially Fatal: Anaphylaxis.
Pregnancy category ::
Drug Mode of Action ::
Dicloxacillin has antimicrobial action similar to benzylpenicillin and includes penicillinase-producing and non-penicillinase-producing staphylococci. It is active against streptococci eg, S. pneumoniae and S. pyogenes is < that of benzylpenicillin, but sufficient to be useful when these organisms are present with penicillin-resistant staphylococci. It is ineffective against E. faecalis. Drug Interactions ::
Probenecid prolongs serum levels of dicloxacillin. Bacteriostatic drugs (e.g. chloramphenicol, tetracyclines) may antagonise the bactericidal effect of dicloxacillin. May reduce anticoagulant response to dicumarol and warfarin. May increase risk of methotrexate toxicity. May diminish the effect of live vaccines (e.g. typhoid vaccine).