The Brand Name LAB Has Generic Salt :: Labetalol 

LAB  Is From Company AKUMENTIS HC. Priced :: Rs. 119

LAB have Labetalol is comes under Sub class Miscellaneous of  Main Class Anti Infectives

Main Medicine Class:: Anti Infectives  Sub Medicine Class :: Miscellaneous 

 Salt Name :  OR Generic Name Form Price : MRP /Probable Packing
Labetalol  TAB  Rs. 119  10
Brand Name Company / Manufacturers Strength Unit Price / 10
 LAB  AKUMENTIS HC.  100MG  10 Rs. 119

Company  Brand Name  Salt Combination Main Medical Class Sub Medical Class
 From AKUMENTIS HC. :: LAB  Labetalol  Anti Infectives Miscellaneous

Indications for Drugs ::

Hypertension, Hypotensive anaesthesia

Drug Dose ::

Adult: PO HTN Initial: 100 mg twice daily, up to 200-400 mg twice daily. Max: 2.4 g/day in 2-4 divided doses. IV Emergency treatment of HTN 50 mg, repeat at 5-min intervals if needed, up to a total dose of 200 mg. HTN in pregnancy Initial: 20 mg/hr, double dose every 30 mins until a favourable response or a dose of 160 mg/hr is reached. HTN after MI Initial: 15 mg/hr, may increase slowly until a favourable response or a dose of 120 mg/hr is achieved. Hypotensive anesth Initial: 10-20 mg, may increase slowly if satisfactory hypotension is not reached after 5 mins.

Contraindication ::

2nd and 3rd degree heart block, cardiogenic shock, obstructive airway disease e.g. bronchial asthma, uncompensated heart failure, severe bradycardia, sick sinus syndrome, Prinzmetal’s angina, severe peripheral arterial disease.

Drug Precautions ::

Phaeochromocytoma, compensated heart failure, nonallergic bronchospasm. Avoid abrupt withdrawal. DM. Hepatic impairment. Perform LFTs. Elderly. Pregnancy and lactation.

Drug Side Effects ::

Orthostatic hypotension, dizziness, fatigue, vertigo, paraesthesia, headache, nasal stuffiness, dyspnoea, diarrhoea, abdominal pain, sexual dysfunction, dyspepsia, nausea, vomiting, scalp tingling, rash, increased transaminases, nightmares, worsening of intermittent claudication. Potentially Fatal: Hepatic injury.

Pregnancy category ::
Pregnancy category

3

Drug Mode of Action ::  

Labetalol competitively inhibits the adrenergic stimulation of ?-receptors w/in the myocardium, bronchial and vascular smooth muscle, and ?1-receptors w/in vascular smooth muscle. It also has some intrinsic ?2-agonist and membrane-stabilising activity.

Drug Interactions ::

Synergistic hypotensive effect w/ halothane. Increased absolute bioavailability w/ cimetidine. Decreased absolute bioavailability w/ glutethimide. Additive hypotensive effect w/ nitroglycerin. Increased incidence of tremor w/ TCAs. Increased risk of bradycardia and heart block w/ Ca channel blocker (e.g. verapamil, diltiazem).

 

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.

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