Article Contents ::
- 1 The Brand Name LOMUSTINE Has Generic Salt :: Lomustine
- 2 LOMUSTINE Is From Company GSK Priced :: Rs. 660
- 3 LOMUSTINE have Lomustine is comes under Sub class Anti Neoplastic Agents of Main Class Anti Neoplastic Agents
- 4 Main Medicine Class:: Anti Neoplastic Agents Sub Medicine Class :: Anti Neoplastic Agents
- 5 Disclaimer ::
- 6 The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.
The Brand Name LOMUSTINE Has Generic Salt :: Lomustine
LOMUSTINE Is From Company GSK Priced :: Rs. 660
LOMUSTINE have Lomustine is comes under Sub class Anti Neoplastic Agents of Main Class Anti Neoplastic Agents
Main Medicine Class:: Anti Neoplastic Agents Sub Medicine Class :: Anti Neoplastic Agents
| Salt Name : OR Generic Name | Form | Price : MRP /Probable | Packing | ||
| Lomustine | CAP | Rs. 660 | 6 |
| Brand Name | Company / Manufacturers | Strength | Unit | Price / 6 |
| LOMUSTINE | GSK | 40MG | 6 | Rs. 660 |
| Company Brand Name | Salt Combination | Main Medical Class | Sub Medical Class |
| From GSK :: LOMUSTINE | Lomustine | Anti Neoplastic Agents | Anti Neoplastic Agents |
Indications for Drugs ::
Brain tumours; Hodgkin’s disease; Lung cancer; Malignant melanoma
Drug Dose ::
Oral Brain tumours, Hodgkin’s disease, resistant or relapsed, Malignant melanoma, Lung cancer Adult: 100-130 mg/m2 as a single dose every 6 wk. Adjust dose according to platelet and leukocyte counts. Compromised marrow function: 100 mg/m2 as a single dose every 6 wk. Child: 75-150 mg/m2 as a single dose every 6 wk. Readjust dose according to platelet and leukocyte counts. Renal impairment: CrCl (ml/min) 10-50 Admin 75% of normal dose. <10 Admin 25-50% of normal dose. Contraindication ::
Pregnancy and lactation.
Drug Precautions ::
Monitor CBC with differential platelet count wkly for at least 6 wk after a dose. Periodically perform pulmonary function studies and LFTs.
Drug Side Effects ::
Pulmonary infiltrates, pulmonary fibrosis, nausea, vomiting, hepatotoxicity, nephrotoxicity, stomatitis, alopecia, disorientation, lethargy, dysarthria, ataxia, visual disturbances. Potentially Fatal: Delayed bone marrow suppression and permanent marrow damage following prolonged use.
Pregnancy category ::
4
Drug Mode of Action ::
Lomustine inhibits the synthesis of DNA and RNA via alkylation although carbamoylation and modification of cellular proteins may also be involved.
Drug Interactions ::
Increased levels/effects with CYP2D6 inhibitors.