Article Contents ::
- 1 The Brand Name MIKAROM Has Generic Salt :: Amikacin
- 2 MIKAROM Is From Company Rhombus Priced :: Rs. N.I.
- 3 MIKAROM have Amikacin is comes under Sub class Aminoglycosides of Main Class Anti Infectives
- 4 Main Medicine Class:: Anti Infectives Sub Medicine Class :: Aminoglycosides
- 5 Disclaimer ::
- 6 The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.
The Brand Name MIKAROM Has Generic Salt :: Amikacin
MIKAROM Is From Company Rhombus Priced :: Rs. N.I.
MIKAROM have Amikacin is comes under Sub class Aminoglycosides of Main Class Anti Infectives
Main Medicine Class:: Anti Infectives Sub Medicine Class :: Aminoglycosides
| Salt Name : OR Generic Name | Form | Price : MRP /Probable | Packing | ||
| Amikacin | INJ | Rs. N.I. | N.I. |
| Brand Name | Company / Manufacturers | Strength | Unit | Price / N.I. |
| MIKAROM | Rhombus | 100/250/500;MG | N.I. | Rs. N.I. |
| Company Brand Name | Salt Combination | Main Medical Class | Sub Medical Class |
| From Rhombus :: MIKAROM | Amikacin | Anti Infectives | Aminoglycosides |
Indications for Drugs ::
Tuberculosis, Complicated and recurrent urinary tract infections, Severe Gram-negative infections, Non-tubercular mycobacterial infections, Bacterial septicemia, Infections of the respiratory tract, Bones and joints, Central nervous system and skin and soft tissue, Intra-abdominal infections, Burns, Postoperative infections, Meningitis, Peritonitis, Neonatal sepsis
Drug Dose ::
Parenteral Uncomplicated urinary tract infections Adult: 250 mg bid, given via IM, IV inj over 2-3 minutes or as IV infusion. Severe Gram-negative infections resistant to gentamicin and tobramycin Adult: 15 mg/kg daily in equally divided doses injected every 8 or 12 hr for 7-10 days. Max: Up to 500 mg every 8 hr in life-threatening infections. Max cumulative dose: 15 g. Doses may be given via IM, slow IV inj over 2-3 minutes or IV infusion. Child: 15 mg/kg daily in equally divided doses injected every 8 or 12 hr for 7-10 days. Neonates: 10 mg/kg daily in 2 divided doses. Impaired renal function: In patient with impaired renal function the daily dose should be reduced and/or the intervals between doses increased to avoid accumulation of the drug. Simple doses schedule for renal impairment is given below: Renal function Dosage schedule Mild impairment 500 mg every 18 hours Moderate impairment 500 mg every 24 hours Severe impairment 250 mg every 24 hours.
Contraindication ::
Pregnancy, perforated ear drum, myasthenia gravis, hypersensitivity.
Drug Precautions ::
Renal impairment; vertigo, tinnitus. Discontinue if signs of ototoxicity, neurotoxicity or hypersensitivity occurs; lactation. Safety has not been established for treatment period >14 days. Monitor renal function before and during treatment.
Drug Side Effects ::
Tinnitus, vertigo; ataxia and overt deafness. Potentially Fatal: Ototoxicity, nephrotoxicity, neuromuscular blockade.
Pregnancy category ::
4
Drug Mode of Action ::
Amikacin binds to 30S ribosomal subunits of susceptible bacteria, thus inhibiting its protein synthesis.
Drug Interactions ::
Amphotericin B may lead to increased nephrotoxicity and reduced clearance of amikacin when used together. Potentially Fatal: Increased ototoxic or nephrotoxic effects with other nephrotoxic or ototoxic drugs. Enhanced neuromuscular blockade with neuromuscular blocking drugs. Increased risk of ototoxicity with potent diuretics.
