The Brand Name NEVACARE Has Generic Salt :: Nevirapine 

NEVACARE  Is From Company CHEMO HC. Priced :: Rs. N.I.

NEVACARE have Nevirapine is comes under Sub class Anti Retrovirals (Drugs for HIV) of  Main Class Anti Infectives

Main Medicine Class:: Anti Infectives  Sub Medicine Class :: Anti Retrovirals (Drugs for HIV) 

Indications for Drugs ::

HIV infection

Drug Dose ::

Oral HIV infection Adult: Combined with other antiretrovirals: 200 mg once daily for the first 14 days; increase to 200 mg bid if rash does not develop. Interrupting the treatment for >7 days necessitate reintroduction at a lower dose for the first 14 days. Child: Combined with other antiretrovirals: 2 mth to 8 yr: 4 mg/kg once daily for the first 14 days; increase to 7 mg/kg bid if no rash is present. 8-16 yr: 4 mg/kg once daily for 14 days followed by 4 mg/kg bid. Max: 400 mg daily. Interrupting the treatment for >7 days necessitate reintroduction at a lower dose for the first 14 days.

Contraindication ::

Hypersensitivity. Lactation. Severe hepatic impairment.

Drug Precautions ::

Pregnancy. Interrupt treatment if severe hepatotoxicity or life-threatening skin reactions develop. Renal or hepatic insufficiency. Monitor liver function periodically.

Drug Side Effects ::

Skin rash, nausea, vomiting, headache, abnormal LFT, fatigue, diarrhoea, abdominal pain. Potentially Fatal: Severe and life-threatening hepatotoxic and skin reactions

Pregnancy category ::

2

Drug Mode of Action ::  

Nevirapine is a non-nucleoside reverse transcriptase inhibitor that acts against HIV-1. It binds directly to reverse transcriptase and thereby blocks the RNA-dependent and DNA-dependent DNA polymerase activities by disrupting the enzyme’s catalytic site.

Drug Interactions ::

Mutually increased levels effects when used with drugs extensively metabolised by CYP3A. Reduced levels/effects of methadone.