Article Contents ::
Details About Generic Salt :: Ornidazole
Main Medicine Class:: Anti Infectives Sub Medicine Class :: Anti Amoebics
| 13K. ANTI-AMOEBICS in 13. ANTI-INFECTIVES |
| ORNIDAZOLE |
| 5-NITROIMIDAZOLE DERIVATIVE | ANTI-AMOEBIC |
| PK: A: Rapid D: Extensively M: Hepatic E: Urine |
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Indications & Dose: AMOEBIASIS PO Adult 500mg BID 5-10 days Child 25mg/kg/day single dose 5-10 days | AMOEBIC DYSENTERY PO Adult 1.5g/day single dose 3 days Child 40mg/kg/day | AMOEBIC DYSENTERY & AMOEBIC LIVER ABSCESS Severe IV Adult Inf: Initially 0.5-1g/day, followed by 500mg q12h 3-6days Child Inf: 20-30mg/kg/day | ANAEROBIC BACTERIAL INFECT IV Adult Initially 0.5-1g/day, followed by 1g/day in 1 or 2 divided doses 5-10 days Child 10mg/kg q12h 5-10 days | GIARDIASIS PO Adult 1-1.5g/day single dose 1-2 days Child 30-40mg/kg/day | TRICHOMONIASIS PO Adult 1.5g/day single dose Child 25mg/kg/day single dose |
| Contra: Hypersensitivity
Precautions: Renal/hepatic impairment, CNS diseases ADR: Serious: thrombophlebitis, seizures, peripheral neuropathy, cholestatic hepatitis, Others: skin rashes, urticaria, pruritus, weakness, diarrhea, headache, ataxia, nausea, vomiting, metallic taste, GI disturbances, constipation, depression, confusion, numbness/tingling DDI: Serious Alcohol causes disulfiram like reaction Diet: After food |
