The Brand Name PENTOREL Has Generic Salt :: Buprenorphine 

PENTOREL  Is From Company Khandelwal Priced :: Rs. 4.33/7.22

PENTOREL have Buprenorphine is comes under Sub class Opioid Analgesics of  Main Class Nervous System

Main Medicine Class:: Nervous System  Sub Medicine Class :: Opioid Analgesics 

 Salt Name :  OR Generic Name Form Price : MRP /Probable Packing
Buprenorphine  INJ  Rs. 4.33/7.22  1ML/2ML
Brand Name Company / Manufacturers Strength Unit Price / 1ML/2ML
 PENTOREL  Khandelwal  0.3MG/ML  1ML/2ML Rs. 4.33/7.22

Company  Brand Name  Salt Combination Main Medical Class Sub Medical Class
 From Khandelwal :: PENTOREL  Buprenorphine  Nervous System Opioid Analgesics

Indications for Drugs ::

Pain, Anaesthesia, Opioid dependence

Drug Dose ::

Adult: Sublingual Moderate to severe pain 200-400 mcg 6-8 hrly. IV Perioperative analgesia 300-450 mcg via slow inj. IV/IM Moderate to severe pain 300-600 mcg 6-8 hrly. IM Anesth premed 300 mcg.

Contraindication ::

Acute alcoholism; convulsive disorders; head injuries; increased intracranial pressure; comatose patients; resp depression and obstructive airway disease; patients on established opioid agonists.

Drug Precautions ::

Hepatic or renal disease; pregnancy, lactation; hypothyroidism; adrenocortical insufficiency; asthma; prostatic hyperplasia; shock; hypotension; inflammatory or obstructive bowel disorders; myasthaenia gravis; infants/neonates. Reduce dose in elderly and debilitated patients. May precipitate withdrawal symptoms in narcotic addicts.

Drug Side Effects ::

Sedation, nausea, dizziness, vertigo, hypotension, miosis, headache, hypoventilation, resp or CNS depression; tachycardia, bradycardia, urinary retention, coma, vomiting, drowsiness, sweating, confusion, dry mouth, diaphoresis, withdrawal syndrome.

Pregnancy category ::
Pregnancy category

3

Drug Mode of Action ::  

Buprenorphine exerts its analgesic effect by binding to the mu-opioid receptors in the CNS. It has a longer duration of analgesic action than morphine. Its partial agonist activity gives it a low level of physical dependence. Buprenorphine and morphine show similar dose-related resp depressant effect.

Drug Interactions ::

Plasma-buprenorphine concentrations may be affected when co-administered with drugs that induce or inhibit cytochrome P450 isoenzyme CYP3A4. Enhanced depressant effects with other CNS depressants e.g. alcohol, anaesthetics, anxiolytics, hypnotics, TCAs and antipsychotics. Potentially Fatal: Diazepam may produce resp and cardiac collapse.

 

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.

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