Article Contents ::
Details About Generic Salt :: Phenylpropanolamine
Main Medicine Class:: #N/A Sub Medicine Class :: #N/A
| 6B. ANTI-HISTAMINES AND NASAL DECONGESTANTS in 6. RESPIRATORY SYSTEM |
| PHENYLPROPANOLAMINE |
| INDIRECTLY-ACTING SYMPATHOMIMETIC | NASAL DECONGESTANT |
| PK: A: Rapid & complete M: Hepatic E: Urine |
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Indications & Dose: NASAL CONGESTION PO Adult Modified release: up to 50mg bid |
| Contra: pheochromocytoma, severe HTN
Precautions: Hyperthyroidism, occlusive vascular disease, CVD, obstructive cardiomyopathy, angle-closure glaucoma, prostate disorders ADR: Serious: hypertensive episodes, dyspnea, difficulty in micturition & urinary retention, piloerection, reflex bradycardia, tachycardia, palpitations, increased cardiac contractility, Others: sweating, vomiting, anxiety, fear, restlessness, insomnia, confusion, headache DDI: Serious Bromocriptine causes HTN, severe headache, seizures & psychosis, Indinavir causes hypertensive crisis, MAOIs causes potentially fatal hypertensive crisis, Amantadine causes psychosis, Theophylline clearance reduces, Methyl dopa/Caffeine/Oxprenolol leads to HTN |