Article Contents ::
Details About Generic Salt :: Primaquine
Main Medicine Class:: #N/A Sub Medicine Class :: #N/A
13J. ANTI-MALARIALS in 13. ANTI-INFECTIVES |
PRIMAQUINE |
8-AMINOQUINOLINE | ANTIMALARIAL |
PK: A: Well absorbed D: Extensive M: Hepatic E: Urine |
Indications & Dose: P. FALCIPARUM MALARIA PO Adult 750µg/kg single dose, max 45mg | RADICAL CURE OF VIVAX OR OVALE MALARIA PO Adult 15mg of base/day 2 wk (15mg base= 26.4mg primaquine phosphate) |
Contra: hypersensitivity, bone marrow depression
Precautions: G6PD deficiency patients ADR: Serious: methemoglobinemia DDI: Serious Primaquine increases risk of toxicity |