Article Contents ::
Details About Generic Salt :: Propantheline
Main Medicine Class:: #N/A Sub Medicine Class :: #N/A
| 10D. DRUGS ACTING ON BLADDER in 10. GENITO-URINARY SYSTEM |
| PROPANTHELINE |
| ANTI-CHOLINERGIC | ANTI-SPASMODIC |
| also comes under 7G. Anti-Spasmodics in 7. Gastrointestinal System, |
| PK: A: Poor M: Small intestine E: Urine |
|
Indications & Dose: ENURESIS/ URINARY INCONTINENCE PO Adult Initially 15mg TID 30-60min before meals & 30mg at HS, max 120mg/day | GI SPASM & ADJUNCT IN PEPTIC ULCER PO Adult Initially 15mg TID 30-60min before meals & 30mg HS, max 120mg/day Child 1 month-12yr: 300µg/kg, max 15mg TID/QID, >12yr: Same as adult dose Elderly 7.5mg TID | HYPERHIDROSIS PO Adult Initially 15mg TID 30-60min before meals & 30mg at HS, max 120mg/day |
| Contra: Hypersensitivity, narrow-angle glaucoma, adhesions between the iris & lens, tachycardia, obstructive GI disease, paralytic ileus, severe UC, toxic megacolon complicating UC, hepatic/renal disease, myasthenia gravis, asthma, thyrotoxicosis, prostatic enlargement
Precautions: Children, elderly, diarrhea/fever ADR: Serious: arrhythmia, hypotension, tachycardia, coma, paralytic ileus, angle-closure glaucoma, anaphylaxis, blurred vision, cycloplegia, mydriasis, increased ocular tension, pulmonary edema, Others: ataxia, insomnia, disorientation, delirium, drowsiness, excitement, dizziness, fever, hallucinations, dryness of mouth with difficulty in swallowing and talking, reduced bronchial secretions, constipation DDI: Serious Ritodrine leads to tachycardia, Phenylephrine results LVF & pulmonary edema Diet: Before food Monitor: HR, BP, pulse, mental status |
