Article Contents ::
Details About Generic Salt :: Salmeterol
Main Medicine Class:: Respiratory System Sub Medicine Class :: Drugs For Asthma,COPD,ARDS
6A. DRUGS FOR ASTHMA/COPD/ARDS in 6. RESPIRATORY SYSTEM |
SALMETEROL |
ß2-ADRENERGIC AGONIST (LONG-ACTING) | BRONCHODILATOR |
PK: A: Variable M: Hepatic E: Feces & urine |
Indications & Dose: ASTHMA Inh Adult 50µg (1 inh) q12h Child >4 yr: Same as adult dose50µg/inhalation | CHRONIC OBSTRUCTIVE PULMONARY DISEASE Maintenance therapy Inh Adult 50µg(1 inh) q12h50µg/inhalation | EXERCISE-INDUCED ASTHMA Inh Adult 50µg (1 inh) at least 30min before exercise Child >4 yr: Same as adult dose50µg/inhalation |
Contra: hypersensitivity, as monotherapy in asthma, status asthmaticus, acute episodes of asthma/COPD
Precautions: CVD, acute episodes of COPD, hepatic impairment, hyperthyroidism, hypokalemia, seizures, glaucoma ADR: Serious: HTN, edema, throat irritation, oropharyngeal candidiasis, immediate bronchospasm, Others: headache, dizziness, sleep disturbance, fever, anxiety, migraine, rash, urticaria, hyperglycemia, nausea, dyspepsia, nasal congestion DDI: Serious TCAs/MAOIs increases effects of drug on vascular system, Thiazides/Loop diuretics increases hypokalemia Monitor: FEV1, peak flow, PFTs, BP, HR |