Details About Generic Salt ::  Trandolapril 

Main Medicine Class:: #N/A   Sub Medicine Class ::  #N/A

4D. ANTI-HYPERTENSIVES in 4. CARDIOVASCULAR SYSTEM
TRANDOLAPRIL
ACEI | ANTI-HYPERTENSIVE
PK: D: 18 L (Vd) M: Hepatic

Indications & Dose: HYPERTENSION PO Adult 1-4mg/day | LEFT VENTRICULAR DYSFUNCTION PO Adult Initially 1mg/day, if tolerated increase dose to 4mg/day | POST MI HEART FAILURE PO Adult Initially 1mg/day, if tolerated increase dose to 4mg/day

Contra: hypersensitivity, history of angioedema

Precautions: CVD, jaundice, renal/hepatic impairment, DM

ADR: Serious: hypotension, agranulocytosis, hepatic necrosis, jaundice, increased liver enzymes, angioedema, syncope, renal failure, MI, cardiogenic shock, URTI, myalgia, Others: hypocalcemia, dyspepsia, edema, back pain, cough, dizziness, diarrhea, headache, fatigue, hyperkalemia, abdominal pain

DDI: Serious Diclofenac increases BP, Antacids reduces drug level

Diet: With/without food

Monitor: Vital signs, CBC, signs & symptoms of bleeding & infect, electrolyte levels, RFT

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