Article Contents ::
Details About Generic Salt :: Trospium
Main Medicine Class:: #N/A Sub Medicine Class :: #N/A
| 10D. DRUGS ACTING ON BLADDER in 10. GENITO-URINARY SYSTEM |
| TROSPIUM |
| ANTI-CHOLINERGIC | URINARY TRACT ANTISPASMODIC |
| PK: A: Poor (10%), decrease with food D: Vd: 395->600 L E: Feces (85%), urine (~6%) |
|
Indications & Dose: IN OVER ACTIVE BLADDER WITH SYMPTOMS OF URINARY FREQUENCY, URGENCY, & INCONTINENCE PO Adult IR: 20mg BID; ER: 60mg OD Elderly >75 yrs: IR: 20mg OD at HS (based on tolerability); ER: 60mg OD |
| Contra: Hypersensitivity, urinary retention, gastric retention, uncontrolled narrow-angle glaucoma
Precautions: Alzheimer’s disease., GI obstructive disorders, controlled narrow-angle glaucoma., moderate or severe hepatic impairment, myasthenia gravis, renal impairment, ulcerative colitis, elderly (=65 yrs) ADR: Serious: tachycardia, dry eye syndrome, blurred vision, nasopharyngitis, Others: dry nose, xerostomia, headache, fatigue, skin rash, xeroderma, constipation, abdominal pain, dyspepsia, flatulence, abdominal distention, nausea/vomiting, urinary retention, UTI, influenza Diet: 1 hr prior to meals/empty stomach |
