Ceftibut

Details About Generic Salt ::  Ceftibut

Main Medicine Class:: Antibiotic,cephalosporin   

(seff-TIE-byoo-ten)
Cedax
Class: Antibiotic/cephalosporin

 

Drugs Class ::

 Action Inhibits mucopeptide synthesis in bacterial cell wall.

Indications for Drugs ::

 Indications Treatment of pharyngitis/tonsillitis caused by S. pyogenes, otitis media caused by M. catarrhalis, H. influenzae (including beta-lactamase-producing strains) or S. pyogenes, and acute bacterial exacerbation of chronic bronchitis caused by S. pneumoniae (penicillin-susceptible strains), H. influenzae (including betalactamase-producing strains) or M. catarrhalis (including beta-lactamase-producing strains).

Drug Dose ::

 Route/Dosage

ADULTS & CHILDREN ³ 12 YR: PO 400 mg QD for 10 days. CHILDREN < 12 YR: PO 9 mg/kg QD (maximum 400 mg) for 10 days. Give suspension 2 hours before or 1 hour after a meal.

Contraindication ::

 Contraindications Hypersensitivity to cephalosporins.

Drug Precautions ::

 Interactions None well documented.

 Lab Test Interferences May cause false-positive urine glucose test results with Benedict’s solution, Fehling’s solution or Clinitest tablets, but not with enzyme-based tests (eg, Clinistix, Test-tape); false-positive test results for proteinuria with acid and denaturization-precipitation tests; false-positive direct Coombs’ test results in certain patients (eg, those with azotemia); false elevations in urinary 17-k

PATIENT CARE CONSIDERATIONS


Drug Side Effects ::

 Interactions None well documented.

 Lab Test Interferences May cause false-positive urine glucose test results with Benedict’s solution, Fehling’s solution or Clinitest tablets, but not with enzyme-based tests (eg, Clinistix, Test-tape); false-positive test results for proteinuria with acid and denaturization-precipitation tests; false-positive direct Coombs’ test results in certain patients (eg, those with azotemia); false elevations in urinary 17-k

PATIENT CARE CONSIDERATIONS


 Administration/Storage

  • Administer oral suspension 2 hours before or 1 hour after meal.
  • After mixing, the suspension may be kept for 14 days stored in refrigerator. Keep tightly closed. Shake well before use. Capsules may be stored at room temperature.

 Assessment/Interventions

  • Assess for hypersensitivity reaction or previous penicillin allergy.
  • Assess renal function prior to starting therapy.
  • Obtain specimens for culture and sensitivity before beginning therapy and periodically during treatment.
  • Monitor for signs of infection, especially fever, and for positive response to antibiotic therapy.
  • Assess for signs and symptoms of anaphylaxis. Have resuscitation equipment available.
  • Assess for signs of superinfection, such as vaginitis or stomatitis.
  • Assess for severe diarrhea with blood or pus, which may be symptom of pseudomembranous colitis. Symptoms may occur after antibiotic treatment is discontinued.
OVERDOSAGE: SIGNS & SYMPTOMS
  Seizures

 Patient/Family Education

  • Inform diabetic patients that oral suspension contains 1 gm sucrose/teaspoon of suspension.
  • Instruct patient to complete full course of therapy.
  • Have patient take drug with food or milk to avoid GI upset.
  • Notify healthcare provider if patient has penicillin allergy or cephalosporin allergy.
  • Notify healthcare provider of nausea, vomiting or diarrhea, especially if severe or contains blood, mucus or pus.
  • Remind diabetic patient to use an enzyme-based test for urine glucose or may otherwise obtain a false-positive result.
  • Remind patient to check body temperature daily. If fever persists for more than a few days or if high fever (> 102°F) or shaking chills are noted, physician should be notified.
  • Instruct patient to report signs of superinfection: black “furry” tongue, white patches in mouth, foul-smelling stools, vaginal itching or discharge.
  • Instruct patient to seek emergency care if he or she experiences wheezing or difficulty breathing.

Drug Mode of Action ::  

 Action Inhibits mucopeptide synthesis in bacterial cell wall.

Drug Interactions ::

 Interactions None well documented.

Drug Assesment ::

 Assessment/Interventions

  • Assess for hypersensitivity reaction or previous penicillin allergy.
  • Assess renal function prior to starting therapy.
  • Obtain specimens for culture and sensitivity before beginning therapy and periodically during treatment.
  • Monitor for signs of infection, especially fever, and for positive response to antibiotic therapy.
  • Assess for signs and symptoms of anaphylaxis. Have resuscitation equipment available.
  • Assess for signs of superinfection, such as vaginitis or stomatitis.
  • Assess for severe diarrhea with blood or pus, which may be symptom of pseudomembranous colitis. Symptoms may occur after antibiotic treatment is discontinued.
OVERDOSAGE: SIGNS & SYMPTOMS
  Seizures

Drug Storage/Management ::

 Administration/Storage

  • Administer oral suspension 2 hours before or 1 hour after meal.
  • After mixing, the suspension may be kept for 14 days stored in refrigerator. Keep tightly closed. Shake well before use. Capsules may be stored at room temperature.

Drug Notes ::

 Patient/Family Education

  • Inform diabetic patients that oral suspension contains 1 gm sucrose/teaspoon of suspension.
  • Instruct patient to complete full course of therapy.
  • Have patient take drug with food or milk to avoid GI upset.
  • Notify healthcare provider if patient has penicillin allergy or cephalosporin allergy.
  • Notify healthcare provider of nausea, vomiting or diarrhea, especially if severe or contains blood, mucus or pus.
  • Remind diabetic patient to use an enzyme-based test for urine glucose or may otherwise obtain a false-positive result.
  • Remind patient to check body temperature daily. If fever persists for more than a few days or if high fever (> 102°F) or shaking chills are noted, physician should be notified.
  • Instruct patient to report signs of superinfection: black “furry” tongue, white patches in mouth, foul-smelling stools, vaginal itching or discharge.
  • Instruct patient to seek emergency care if he or she experiences wheezing or difficulty breathing.

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.

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