Details About Generic Salt ::  Enoxacin

Main Medicine Class:: Antibiotic,Fluoroquinolone   

(en-OX-uh-SIN)

Penetrex

Class: Antibiotic/Fluoroquinolone

Drugs Class ::

 Action Interferes with microbial DNA synthesis.

Indications for Drugs ::

 Indications Treatment of urinary tract infections caused by susceptible organisms; treatment of sexually transmitted disease caused by Neisseria gonorrhoeae.

Drug Dose ::

 Route/Dosage

Urinary Tract Infections

ADULTS: PO 200–400 mg q 12 hr for 7–14 days.

Sexually Transmitted Diseases

ADULTS: PO 400 mg as single dose.

Contraindication ::

 Contraindications Hypersensitivity to fluoroquinolones.

Drug Precautions ::

 Precautions

Pregnancy: Category C. Lactation: Excreted in breast milk. Children: Contraindicated in children. CNS disorders: Use drug with caution in patients predisposed to seizures or with other CNS disorders. Convulsions: CNS stimulation can occur; use drug with caution in patients with known or suspected CNS disorders. Hypersensitivity: Serious and potentially fatal reactions have occurred. Discontinue drug if allergic reaction occurs. Pseudomembranous colitis: Consider possibility in patients in whom diarrhea develops subsequent to administration of antibacterial agents. Renal impairment: Reduced clearance may occur; dosage adjustment may be required. Superinfection: Use of antibiotics may result in bacterial or fungal overgrowth of nonsusceptible microorganisms.

Drug Side Effects ::

 Adverse Reactions

CNS: Headache; dizziness; insomnia; vertigo. DERM: Pruritus; photosensitivity. EENT: Tinnitus; unusual taste in mouth. GI: Diarrhea; nausea; vomiting; abdominal pain or discomfort; dyspepsia; heartburn.

Drug Mode of Action ::  

 Action Interferes with microbial DNA synthesis.

Drug Interactions ::

 Interactions

Antacids, iron salts, zinc salts, sucralfate, bismuth subsalicylate: May decrease oral absorption of fluoroquinolone. Caffeine: Reduces clearance of caffeine. Digoxin: May increase digoxin levels. Theophylline: Can cause decreased clearance and increased plasma levels of theophylline, which may result in toxicity.

Drug Assesment ::

 Assessment/Interventions

• Obtain patient history, including drug history and any known allergies.
• Determine baseline WBC and BUN.
• Assess renal and liver function.
• Monitor temperature.
• Monitor patient for signs and symptoms of hypersensitivity.
• Inform physician of signs and symptoms of superinfection (eg, black furry tongue, white patches in mouth, foul-smelling stool).
• If GI disturbances develop, withhold drug and notify physician.
• If photosensitivity occurs, withhold drug and notify physician.

Drug Storage/Management ::

 Administration/Storage

• Do not administer with antacids.
• Administer medication at least 1 hr before or 2 hr after meal.
• Encourage patient to increase fluid intake.

Drug Notes ::

 Patient/Family Education

• Instruct patient to take drug at least 1 hr before meals or 2 hr after meals.
• Advise patient not to take medication with antacids.
• Caution patient to avoid exposure to sunlight and to use sunscreen or wear protective clothing to avoid photosensitivity reaction.
• Instruct patient to increase fluid intake and to restrict or eliminate caffeine intake.
• Advise patient to report any visual changes, agitation, or rash to physician.
• Instruct patient to report any additional infections after completion of medication to physician.
• Tell patient to notify physician if diarrhea develops.
• Advise patient that drug may cause dizziness and lightheadedness and to use caution while driving or performing other tasks requiring mental alertness.

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.