Details About Generic Salt ::  Lomeflox

Main Medicine Class:: Antibiotic,fluoroquinolone   

(low-MUH-FLOX-uh-sin HIGH-droe-KLOR-ide)
Class: Antibiotic/fluoroquinolone


Drugs Class ::

 Action Interferes with microbial DNA synthesis.

Indications for Drugs ::

 Indications Treatment of infections of the lower respiratory tract and urinary tract caused by susceptible organisms; prevention of urinary tract infections in patients undergoing transurethral or transrectal procedures.

Drug Dose ::


ADULTS: PO 400 mg qid for 3 to 14 days.

Surgical Prophylaxis

PO 400 mg 2 to 6 hr preoperatively.

Contraindication ::

 Contraindications Hypersensitivity to fluoroquinolones or quinolone antibiotics; tendonitis or tendon rupture associated with quinolone use.

Drug Precautions ::


Pregnancy: Category C. Lactation: Excreted in breast milk. Children: Do not use in children < 18 yr. Elderly: Clearance may be decreased. Chronic bronchitis: Lomefloxacin is not indicated for empiric treatment of acute bacterial exacerbation of chronic bronchitis when Streptococcus pneumoniae is probable pathogen. Convulsions: CNS stimulation can occur; use with caution in patients with known or suspected CNS disorders. Hypersensitivity reactions: Serious and potentially fatal reactions have occurred. Discontinue if allergic reaction occurs. Pseudomembranous colitis: Consider in patients who develop diarrhea. Renal impairment: Reduced clearance may occur; adjust dose accordingly. Superinfection: Use may result in bacterial or fungal overgrowth.


Drug Side Effects ::

 Adverse Reactions

CNS: Headache; dizziness. DERM: Photosensitivity. GI: Diarrhea; nausea.

Drug Mode of Action ::  

 Action Interferes with microbial DNA synthesis.

Drug Interactions ::


Antacids, iron salts, zinc salts, sucralfate, didanosine: Decreased oral absorption of lomefloxacin. Stagger administration times. Antineoplastic agents: Decreased lomefloxacin serum levels. Probenecid: Decreased renal elimination of lomefloxacin.

Drug Assesment ::


  • Obtain patient history, including drug history and any known allergies, especially to fluoroquinolones or quinolone antibiotics. Note renal impairment.
  • Assess patient for signs of infection before beginning treatment.
  • Obtain specimens for culture and sensitivity before beginning treatment.
  • Take baseline vital signs and reassess at least bid.
  • Monitor I&O.
  • Assess for symptoms of superinfection, such as vaginitis or stomatitis.
  Renal failure (severely decreased urine output, weight gain, confusion, dry flaky skin), tremor, seizures

Drug Storage/Management ::


  • May be administered with or without food; however, absorption is more rapid on empty stomach.
  • Do not give antacids, sucralfate, iron or zinc-containing products within 2 hr before or after medication.
  • Store at room temperature in tightly closed, light-resistant container.

Drug Notes ::

 Patient/Family Education

  • Instruct patient to continue taking medication until completed, even if signs and symptoms of infection abate.
  • Warn patient not to take antacids or vitamins < 4 hr before or 2 hr after taking medication.
  • Encourage patient to drink plenty of fluids, especially citrus fruit juices and cranberry juice.
  • Advise patient that drug may cause dizziness and to use caution while driving or performing other tasks requiring mental alertness.
  • Caution patient to avoid prolonged exposure to sunlight even when using sunscreens or sunblocks, and to wear protective clothing to avoid photosensitivity reaction.
  • Instruct patient to stop treatment and inform physician if experiencing pain, inflammation, or rupture of tendon, and to rest or refrain from exercise until diagnosis of tendonitis or tendon rupture is excluded.

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.


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