Details About Generic Salt ::  Temazepa

Main Medicine Class:: Sedative Hypnotic,Benzodiazepine   

(tem-AZE-uh-pam)

Restoril,  Apo-Temazepam, Dom-Temazepam, Gen-Temazepam, Novo-Temazepam, Nu-Temazepam, PMS-Temazepam

Class: Sedative Hypnotic/Benzodiazepine

Drugs Class ::

 Action Potentiates action of GABA (gamma-aminobutyric acid), an inhibitory neurotransmitter, resulting in increased neuronal inhibition and CNS depression, especially in limbic system and reticular formation.

Indications for Drugs ::

 Indications Short-term management of insomnia.

Drug Dose ::

 Route/Dosage

ADULTS: PO 7.5–30 mg at bedtime; individualize. ELDERLY OR DEBILITATED PATIENTS: PO 15 mg until individual response is determined.

Contraindication ::

 Contraindications Hypersensitivity to benzodiazepines; pregnancy.

Drug Precautions ::

 Precautions

Pregnancy: Category X. Lactation: Similar drugs excreted in breast milk. Children: Not for use in children < 18 yr. Elderly/debilitated: Increased side effects; start with lowest dose. Anterograde amnesia: Has occurred with similar drugs. Alcohol may increase risk. Dependence/withdrawal: Prolonged use can lead to psychological or physical dependence. Withdrawal syndrome may occur; dose must be tapered gradually. Renal or hepatic impairment: Observe caution. Abnormal liver function test results and blood dyscrasias have occurred.

Drug Side Effects ::

 Adverse Reactions

CV: Palpitations; tachycardia. CNS: Drowsiness; dizziness; lethargy; confusion; euphoria; weakness; falling; ataxia; hallucinations; paradoxical reactions (eg, excitement, agitation); headache; memory impairment. EENT: Blurred vision; difficulty focusing. GI: Anorexia; diarrhea; abdominal cramping; constipation; nausea; vomiting. HEMA; Leukopenia; agranulocytopenia. OTHER: Tolerance; physical and psychological dependence; slurred speech; elevated AST, ALT, bilirubin.

Drug Mode of Action ::  

 Action Potentiates action of GABA (gamma-aminobutyric acid), an inhibitory neurotransmitter, resulting in increased neuronal inhibition and CNS depression, especially in limbic system and reticular formation.

Drug Interactions ::

 Interactions

Alcohol, other CNS depressants: Additive CNS depressant effects. Digoxin: Serum digoxin concentrations may increase. Theophylline: May antagonize sedative effects.

Drug Assesment ::

 Assessment/Interventions

• Obtain patient history, including drug history and any known allergies. Note drug dependence and potential for suicide.
• Assess type of sleep difficulty (eg, falling asleep, remaining asleep, etc.).
• Provide safety measures (siderails up, nightlight, call bell accessible) and assist with ambulation.
• Carefully document response to initial dose; dose may be increased to 30 mg.
• Assess results of baseline liver and kidney function test and complete blood count with differential. Periodically reevaluate these values throughout long-term therapy.
• Assess and document mental and psychological parameters such as hallucinations, dreaming and nightmares, depression, euphoria, apprehension affect, mood and memory. Report potential problems to physician.
• Notify physician if any of these symptoms occur: palpitations, increased heart rate, visual disturbances along with nausea and vomiting or headache, excitation, dermatitis, sweating, flushing, pruritus, body or joint pain, tinnitus and nasal congestion.

Drug Storage/Management ::

 Administration/Storage

• Administer ½ hr before bedtime with full glass of water.
• If GI upset occurs, administer with food.
• Store in tightly closed container at cool temperature.

Drug Notes ::

 Patient/Family Education

• Caution patient that this medication must not be taken during pregnancy or when pregnancy is possible. Advise patient to use reliable form of birth control while taking this drug.
• Discuss with patient ways to facilitate sleep: quiet, avoidance of caffeine and nicotine, warm baths, deep breathing, relaxation techniques.
• Explain that disturbed nocturnal sleep may occur for first or second night after discontinuing use.
• Tell patient not to discontinue medication abruptly after prolonged therapy (> 2 wk).
• Explain safety precautions with regard to falls, especially for elderly and debilitated patients.
• Instruct patient to report these symptoms to physician: visual disturbances, abdominal pain or palpitations, fever, sore throat, bruising, rash, jaundice, unusual bleeding.
• Advise patient to avoid intake of alcoholic beverages or other CNS depressants.
• Caution patient that drug may cause drowsiness and to use caution while driving or performing other tasks requiring mental alertness.

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.