Article Contents ::
Details About Generic Salt :: Amisulpride
Main Medicine Class:: Nervous System Sub Medicine Class :: Anti Psychotics
1E. ANTI-PSYCHOTICS in 1. NERVOUS SYSTEM |
AMISULPRIDE |
SELECTIVE D2/D3 RECEPTOR ANTAGONIST | ATYPICAL ANTI-PSYCHOTIC |
PK: A: GIT M: Hepatic E: Urine |
Indications & Dose: ACUTE PSYCHOTIC EPISODES PO Adult 400-800mg in 2divided doses, may be increased to 1.2g/day | IM Adult 400mg/day |
Contra: Pheochromocytoma, prolactin-dependent tumours
Precautions: Elderly, abrupt withdrawal, severe renal impairment, history of epilepsy/parkinson’s disease ADR: Serious: hyperprolactinemia, galactorrhea, amenorrhea, impaired fertility, gynecomastia, tardive dyskinesia, HTN, QT prolongation, torsade de pointes, NMS, Others: insomnia, constipation, drowsiness, nausea, vomiting DDI: Serious Lithium increases drug adverse effects |