The Brand Name APILYTE Has Generic Salt :: ORAL 

APILYTE  Is From Company ALICON PH. Priced :: Rs. 13

APILYTE have ORAL is comes under Sub class #N/A of  Main Class #N/A

Main Medicine Class:: #N/A  Sub Medicine Class :: #N/A 

Indications for Drugs ::

Cholera, Protection against cholera in adult & children >2 yr.

Drug Dose ::

Oral Active immunisation against cholera Adult: For primary vaccination schedule: Given as a suspension (in doses of 3 ml, mixed with sodium hydrogen carbonate solution): 2 doses, at wkly intervals. Complete immunisation 1 wk prior to potential exposure. If >6 wk have elapsed between doses, primary immunisation course should be re-initiated. A single booster dose may be given after 2 yr to maintain protection. Child: For primary vaccination schedule: Given as a suspension (in doses of 3 ml, mixed with sodium hydrogen carbonate solution): 2-6 yr: 3 doses, at wkly intervals; >6 yr: 2 doses, at wkly intervals. Complete immunisation 1 wk prior to potential exposure. If >6 wk have elapsed between doses, primary immunisation course should be re-initiated. A single booster dose may be given after 6 mth (2-6 yr) or 2 yr (>6 yr), depending on the age of the patient to maintain protection.

Contraindication ::

Hypersensitivity. Acute stomach disorder or infection w/ fever (postpone vaccination).

Drug Precautions ::

There are only limited data on safety and immunogenicity of the vaccine in children aged 1 to 2 years and protective efficacy has not been studied. Therefore, this is not recommended to be used in children less than 2 years of age. There are only very limited data on protective efficacy of the vaccine in subjects aged 65 years and more. No clinical data on protective efficacy of this vaccine against cholera after administration of booster doses are available. This vaccine confers protection specific to Vibrio cholerae serogroup O1. Immunisation does not protect against V. cholerae serogroup O139 or other species of Vibrio. In subjects infected with HIV, limited data are available on immunogenicity and safety of the vaccine. Vaccine protective efficacy has not been studied. Immunisation of HIV infected subjects could result in transient increases of viral load. Dukoral may not induce protective antibody levels in subjects with advanced HIV disease. Formaldehyde is used during the manufacturing process and trace amounts may be present in the final product. Caution should be taken in subjects with known hypersensitivity to formaldehyde. The vaccine does not provide complete protection and it is important to adhere to standard protective measures to avoid cholera.

Drug Side Effects ::

GI disturbances, headache.

Pregnancy category ::

0

Drug Mode of Action ::  

Cholera vaccine is available as oral preparations containing either live attenuated or inactivated strains. Oral cholera vaccines appear to be more effective than parenteral vaccines. It may be used in adults and children aged ?2 yr who are traveling to areas of risk.

Drug Interactions ::

Not to be used within 3 wk of immunoglobulin admin. Reduced response may occur in patients who are concurrently receiving immunosuppressant treatment e.g. antineoplastics, corticosteroids at therapeutic doses. Oral, encapsulated typhoid vaccine should not be admin within 8 hr of cholera vaccine admin.