Article Contents ::
Details About Generic Salt :: Astemizole
Main Medicine Class:: Respiratory System Sub Medicine Class :: Anti Histamines and Nasal Decongestants
| 6B. ANTI-HISTAMINES AND NASAL DECONGESTANTS in 6. RESPIRATORY SYSTEM |
| ASTEMIZOLE |
| H1-BLOCKER (SECOND GENERATION) | ANTI-ALLERGIC |
| PK: A: Rapid M: Hepatic E: Urine, feces |
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Indications & Dose: ALLERGIC RHINITIS PO Child 6-12yr: 5mg OD |
| Contra: cardiac/significant hepatic disease, drugs, hypokalaemia/electrolyte imbalances
Precautions: polypharmacy ADR: Serious: ventricular arrhythmias, Others: increased appetite & weight gain DDI: Serious HIV protease inhibitors leads to arrhythmias, Azoles leads to Torsade de pointes, Macrolides leads to Torsade de pointes arrhythmias, Nefazodone prolongs QT interval |