The Brand Name BAROZINE Has Generic Salt :: Cinnarizine 

BAROZINE  Is From Company Baroque Priced :: Rs. N.I.

BAROZINE have Cinnarizine is comes under Sub class Anti Migraine , Anti Vertigo Drugs of  Main Class Nervous System

Main Medicine Class:: Nervous System  Sub Medicine Class :: Anti Migraine , Anti Vertigo Drugs 

Indications for Drugs ::

Nausea and vomiting, motion sickness, vertigo, meniere’s disease, peripheral vascular diseases, cerebrovascular disorders, vestibular disorders

Drug Dose ::

Adult: PO 15 to 30 mg three times daily. Peripheral vascular diseases 75 mg 2-3 times/day. Motion sickness 30 mg 2 hr before travel and 15 mg 8 hrly during travel if needed. Cerebrovascular disorders 75 mg 1-3 times/day. Vertigo and vestibular disorders 30 mg 3 times/day. Children (5 to 12 years): Half of the adult dose.

Contraindication ::

Proven hypersensitivity to the drug. Parkinson’s disease. Childn and neonates.

Drug Precautions ::

Hypotension; pregnancy; lactation; elderly. May impair ability to drive or operate machineries.

Drug Side Effects ::

Extrapyramidal symptoms sometimes associated with severe depression. Drowsiness, headache, GI upsets, unsteadiness, headache; rarely skin and hypersensitivity reactions, dry mouth, blurred vision, urinary difficulty or retention, constipation and increased gastric reflux, fatigue. Hypolipidaemic effect.

Pregnancy category ::

3

Drug Mode of Action ::  

Cinnarizine has calcium-channel blocking activity selective for arterial smooth muscle. It also has some antihistamine activity. Cinnarizine acts as a labyrinthine sedative. It also improves microcirculation by reducing ischaemia-induced blood viscosity.

Drug Interactions ::

CNS depressant effect enhanced with alcohol. Action potentiated by domperidone.