Article Contents ::
Details About Generic Salt :: Caffeine
Main Medicine Class:: #N/A Sub Medicine Class :: #N/A
| 6A. DRUGS FOR ASTHMA/COPD/ARDS in 6. RESPIRATORY SYSTEM |
| CAFFEINE |
| CNS STIMULANT |
| PK: A: Rapid & readily D: Vd: 0.8-0.9L/kg (Neonates), 0.6 L/kg (child >9 months to adults) M: Hepatic E: urine |
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Indications & Dose: CNS STIMULANT Mild PO Adult 50-100mg, upto 200mg. Not be taken more often than q3hrs | NEONATAL APNEA OF PREMATURITY IV/PO Child Loading dose: 10-20mg/kg as citrate, followed by MD 5mg/kg/day |
| Contra: Hypersensitivity
Precautions: history of peptic ulcer/GERD, impaired renal/hepatic function, seizures, CVD, symptomatic cardiac arrhythmias, anxiety ADR: Serious: increased IOP, angina, arrhythmia, sinus tachycardia, Others: agitation, delirium, dizziness, hallucinations, headache, insomnia, irritability, urticaria, gastritis, diuresis DDI: Others Paracetamol bioavailability either increases/decreases, Phenobarbital effects are diminishes/abolishes, CYP1A2 Inhibitors/Atomoxetine increases caffeine levels, Stiripentol inhibits caffeine metabolism, Sympathomimetics levels increases, Levodopa rate of absorption increases |