Article Contents ::
Details About Generic Salt :: Entecavir
| 13N. ANTI-RETROVIRALS (DRUGS FOR HIV) in 13. ANTI-INFECTIVES |
| ENTECAVIR |
| GUANOSINE NUCLEOSIDE ANALOGUE | ANTI-VIRAL |
| PK: A: Rapid D: Extensive M: Partially hepatic E: Urine |
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Indications & Dose: DECOMPENSATED LIVER DISEASE PO Adult 1mg OD | LAMIVUDINE-RESISTANT VIREMIA PO Adult 1mg OD | NUCLEOSIDE TREATMENT-NAIVE PO Adult 0.5mg OD |
| Precautions: Renal impairment, patients receiving drugs that reduces renal function, hepatomegaly/other risk factors for liver disease
ADR: Serious: exacerbation of hepatitis, severe hepatomegaly steatosis, lactic acidosis, peripheral edema, Others: headache, nausea, fatigue, dizziness, diarrhea, dyspepsia, insomnia, somnolence, vomiting, raised liver enzyme levels DDI: Serious Ribavirin/Ganciclovir/Valganciclovir increases drug efficacy Diet: On empty stomach Monitor: HIV status, LFTs, renal function, HIV viral load, CD4 count |