The Brand Name INDOFLAM TR Has Generic Salt :: Indomethacin 

INDOFLAM TR  Is From Company Zydus Cadila Priced :: Rs. 10.81/40.92

INDOFLAM TR have Indomethacin is comes under Sub class Analgesics , Anti inflammatory Drugs of  Main Class Musculoskeletal Disorders , Pain

Main Medicine Class:: Musculoskeletal Disorders , Pain  Sub Medicine Class :: Analgesics , Anti inflammatory Drugs 

 Salt Name :  OR Generic Name Form Price : MRP /Probable Packing
Indomethacin  CAP  Rs. 10.81/40.92  10-Oct
Brand Name Company / Manufacturers Strength Unit Price / 10-Oct
 INDOFLAM TR  Zydus Cadila  25/75;MG  10-Oct Rs. 10.81/40.92

Company  Brand Name  Salt Combination Main Medical Class Sub Medical Class
 From Zydus Cadila :: INDOFLAM TR  Indomethacin  Musculoskeletal Disorders , Pain Analgesics , Anti inflammatory Drugs

Indications for Drugs ::

Rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis (degenerative joint disease), gout, acute non-articular rheumatism (bursitis, synovitis, tendinitis).

Drug Dose ::

By mouth, rheumatic disease, 50-200 mg daily in divided doses, with food. Acute gout, 150-200 mg daily in divided doses. Dismenorrhea, upto 75 mg daily. Children: Not recommended Rectal Pain and inflammation associated with musculoskeletal and joint disorders Adult: As supp: 100 mg to be inserted at night and repeated in the morning if necessary.

Contraindication ::

Indomethacin is contraindicated in patients with ulcer, gastritis, active ulcerative colitis, and should be used with caution in patients with a history of these disorders. It is also contraindicated in previously hypersensitive patient.

Drug Precautions ::

Patient w/ known CV disease or risk factors for CV disease, fluid retention, history of GI disease (e.g. bleeding or ulcers), history of mental depression or other psychiatric disorder, epilepsy, or parkinsonian syndrome; existing infection that is adequately controlled. May mask signs and symptoms of infection. Hepatic and renal impairment. Elderly, childn. Pregnancy and lactation.

Drug Side Effects ::

Headaches, usually in the morning and mild vertigo may occur during the early weeks of therapy. These symptoms are transient and usually disappear with continued use or by reduction of the dose. Gastrointestinal reactions such as nausea, vomiting, diarrhoea, epigastric and abdominal pain are often due to large doses of the drug and disappear when the dose is reduced.

Pregnancy category ::
Pregnancy category


Drug Mode of Action ::  

Indometacin, an indole acetic acid derivative has anti-inflammatory, analgesic and antipyretic actions. It reversibly inhibits cyclooxygenase-1 and -2 (COX-1 and -2) enzymes, thus resulting in reduced synthesis of prostaglandin precursors.

Drug Interactions ::

May increase plasma levels of methotrexate. Increased risk of GI bleeding w/ warfarin. May reduce hypotensive effects of hydralazine, furosemide, ?-blockers (e.g. atenolol, propranolol, oxprenolol), or thiazide diuretics. Increased risk of hyperkalaemia w/ K-sparing diuretics, ACE inhibitors, K supplements. May increase nephrotoxic effects of ciclosporin or triamterene. Increase plasma concentration w/ probenecid. May increase plasma levels of aminoglycoside (e.g. amikacin, gentamicin) in premature neonates. May enhance antipsychotic effect (e.g. severe drowsiness and confusion) of haloperidol. Al- or Mg-containing antacids may reduce GI disorders of indometacin. Potentially Fatal: Diflunisal decreases renal clearance and increases plasma concentrations of indometacin which leads to fatal GI haemorrhage.


Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.


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