Article Contents ::
Details About Generic Salt :: Loratadine
Main Medicine Class:: Respiratory System Sub Medicine Class :: Anti Histamines and Nasal Decongestants
| 6B. ANTI-HISTAMINES AND NASAL DECONGESTANTS in 6. RESPIRATORY SYSTEM |
| LORATADINE |
| H1-ANTAGONIST (SECOND GENERATION) | ANTI-ALLERGIC |
| PK: A: Rapid M: Hepatic E: Urine (40%), feces (40%) as metabolites |
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Indications & Dose: ALLERGIC RHINITIS Symptomatic therapy PO Adult 10mg/day (self medication) Child 2-6 yr: Syrup 5mg/day, >6 yr: Same as adult dose (self medication) | IDIOPATHIC URTICARIA Chronic PO Adult 10mg/day (self medication) Child 2-5 yr: Syrup 5mg/day (under clinician supervision), >6 yr: Same as adult dose (self medication) |
| Contra: Hypersensitivity
Precautions: Renal/hepatic impairment ADR: Serious: Hypotension, HTN, supraventricular tachyarrhythmia, syncope, tachycardia, tinnitus, conjunctivitis, blurred vision, bronchospasm, chest pain, bronchitis, arthralgia, Others: back pain, urinary incontinence, urinary retention, vaginitis, urticaria, weakness, Headache, somnolence, fatigue, xerostomia, nervousness, malaise, rash, abdominal pain, agitation, altered lacrimation, micturition, salivation, taste, anorexia, anxiety DDI: Serious Acenocoumarol anticoagulant effects reduces, Amiodarone causes cardiac abnormalities, Ketoconazole increases QTc interval, Cimetidine raises drug levels Diet: On empty stomach |
