Article Contents ::
- 1 The Brand Name NEOFLOX Has Generic Salt :: FLUCLOXACILLIN
- 2 NEOFLOX Is From Company Neon Priced :: Rs. N.I.
- 3 NEOFLOX have FLUCLOXACILLIN is comes under Sub class #N/A of Main Class #N/A
- 4 Main Medicine Class:: #N/A Sub Medicine Class :: #N/A
- 5 Disclaimer ::
- 6 The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.
The Brand Name NEOFLOX Has Generic Salt :: FLUCLOXACILLIN
NEOFLOX Is From Company Neon Priced :: Rs. N.I.
NEOFLOX have FLUCLOXACILLIN is comes under Sub class #N/A of Main Class #N/A
Main Medicine Class:: #N/A Sub Medicine Class :: #N/A
|Salt Name : OR Generic Name||Form||Price : MRP /Probable||Packing|
Indications for Drugs ::
Pneumonia, Burns, Meningitis, Endocarditis, Sinusitis, Septicaemia, Tonsillitis, Surgical Prophylaxis, Staphylococcal skin infections, Boils, Osteomyelitis, Enteritis,Wounds, Abscesses, Infected eczema, Infected acne
Drug Dose ::
Adults (including elderly patients): Oral: 250-500mg three to four times a day. Oral doses should be administered 1 hour before meal Children 2-10 years: Half of adult dose Under 2 years: One fourth of adult dose Children have been given doses of 12.5-25 mg/kg body weight four times a day. IV 0.25-1 g 4 times/day, may double in severe cases. Up to 8 g/day in 3-4 divided doses may be given for osteomyelitis. Up to 8 g/day in 4 divided doses for endocarditis in patients weighing <85 kg and 12 g/day in 6 divided doses for patients weighing >85 kg. Renal impairment: CrCl (ml/min) <10 Dosage adjustment may be necessary. Contraindication ::
Hypersensitivity to penicillins. Porphyria.
Drug Precautions ::
Very high doses in poor renal function (risk of neurotoxicity) or heart failure. Avoid contact, skin sensitization may occur. Monitor serum potassium concentration, renal and haematological status. Spirochete infections particularly syphilis; suprainfection with penicillin-resistant organisms with prolonged use; avoid intrathecal route; elderly. Hepatic impairment.
Drug Side Effects ::
Hypersensitivity reactions including urticaria; fever; joint pains; rashes; angioedema; serum sickness-like reactions; haemolytic anaemia; interstitial nephritis; neutropenia; thrombocytopenia; CNS toxicity including convulsions; diarrhoea; antibiotic-associated colitis; hepatitis, cholestatic jaundice; agranulocytosis; phlebitis (IV infusion). Potentially Fatal: Anaphylaxis. Stevens-Johnson syndrome
Pregnancy category ::
Drug Mode of Action ::
Flucloxacillin inhibits the 3rd and last step of bacterial cell wall synthesis by binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall. It is active against penicillinase-producing and non-penicillinase-producing staphylococci.
Drug Interactions ::
May increase the risk of methotrexate toxicity. May decrease the efficacy of oestrogen-containing OC. Enhanced plasma concentrations w/ probenecid. Bacteriostatic drugs (e.g. chloramphenicol, tetracycline) may interfere w/ the bactericidal effect of flucloxacillin. May prolong bleeding time in patients on oral anticoagulants.