Article Contents ::
- 1 The Brand Name ORTHOCORT Has Generic Salt :: DEFLAZACORT
- 2 ORTHOCORT Is From Company Macleods Priced :: Rs. 46.46
- 3 ORTHOCORT have DEFLAZACORT is comes under Sub class Corticosteroids of Main Class Endocrine,Steroid Hormones , Metabolic System
- 4 Main Medicine Class:: Endocrine,Steroid Hormones , Metabolic System Sub Medicine Class :: Corticosteroids
- 5 Disclaimer ::
The Brand Name ORTHOCORT Has Generic Salt :: DEFLAZACORT
ORTHOCORT Is From Company Macleods Priced :: Rs. 46.46
ORTHOCORT have DEFLAZACORT is comes under Sub class Corticosteroids of Main Class Endocrine,Steroid Hormones , Metabolic System
Main Medicine Class:: Endocrine,Steroid Hormones , Metabolic System Sub Medicine Class :: Corticosteroids
|Salt Name : OR Generic Name||Form||Price : MRP /Probable||Packing|
Indications for Drugs ::
Allergic and inflammatory disorders
Drug Dose ::
Oral Allergic and inflammatory disorders Adult: Initially, up to 120 mg daily. Maintenance: 3-18 mg/day. Child: 0.25-1.5 mg/kg/day given on alternate days. Hepatic impairment: Dose reductions may be needed.
Systemic infection; live virus vaccines in those receiving immunosuppressive doses.
Drug Precautions ::
Adrenal suppression and infection, child, adolescents, elderly, history of TB and steroid myopathy, hypertension, recent MI, CHF, liver failure, renal impairment, DM and glaucoma (including family history), osteoporosis, corneal perforation, severe affective disorders, epilepsy, peptic ulcer, hypothyroidism, pregnancy and lactation.
Drug Side Effects ::
GI disturbances, musculoskeletal, endocrine, neuropsychiatric, ophthalmic, fluid and electrolyte disturbances; susceptible to infection, impaired healing, hypersensitivity, skin atrophy, striae, telangiectasia, acne, myocardial rupture following recent MI, thromboembolism.
Pregnancy category ::
Drug Mode of Action ::
Deflazacort, derived from prednisolone, is a corticosteroid with mainly glucocorticoid activity. An anti-inflammatory dose of 6 mg deflazacort is equiv to 5 mg prednisolone.
Drug Interactions ::
Antacids, ACE inhibitors, acetazolamide, adrenergic neuron blockers, antidiabetics, aspirin, barbiturate, ?-blockers, calcium-channel blockers, carbamazepine, carbenoxolone, cardiac glycosides, clonidine, coumarins, diazoxide, diuretics, erythromycin, hydralazine, ketoconazole, methotrexate, methyldopa, mifepristone, minoxidil, moxonidine, nitrates, nitroprusside, NSAIDs, oestrogens, phenytoin, primidone, rifamycins, ritonavir, somatropin, ?2 sympathomimetics, theophylline, vaccines.