Article Contents ::
- 1 The Brand Name PALZEN Has Generic Salt :: PALONOSETRON
- 2 PALZEN Is From Company Dr.Reddy’S Priced :: Rs. 149
- 3 PALZEN have PALONOSETRON is comes under Sub class Anti Emetics of Main Class Gastrointestinal System
- 4 Main Medicine Class:: Gastrointestinal System Sub Medicine Class :: Anti Emetics
- 5 Disclaimer ::
The Brand Name PALZEN Has Generic Salt :: PALONOSETRON
PALZEN Is From Company Dr.Reddy’S Priced :: Rs. 149
PALZEN have PALONOSETRON is comes under Sub class Anti Emetics of Main Class Gastrointestinal System
Main Medicine Class:: Gastrointestinal System Sub Medicine Class :: Anti Emetics
|Salt Name : OR Generic Name||Form||Price : MRP /Probable||Packing|
Indications for Drugs ::
Chemotherapy-induced nausea and vomiting, Postoperative nausea and vomiting
Drug Dose ::
Adult: IV: Chemotherapy-induced nausea and vomiting 0.25 mg as a single dose 30 mins before chemotherapy. Do not repeat w/in 7 days. Prevention of post-op nausea and vomiting 0.075 mg as a single dose immediately before induction of anesth. PO: 0.5 mg tablet once daily.
History of hypersensitivity.
Drug Precautions ::
Patients with intestinal obstruction or ileus. Rapid inj may lead to temporary visual changes e.g. blurred vision. Patients who have or may develop prolonged QT intervals. Safety and efficacy not established in children <18 yr. Counsel patients who handle skilled tasks e.g. driving may be impaired. Drug Side Effects ::
Headache; flushing; fatigue, dizziness, drowsiness; hiccups; chest pain, tachycardia and bradycardia; diarrhoea, constipation, flatulence; dry mouth; urinary retention; dyspepsia, abdominal pain; changes in BP; asthenia; anxiety, euphoria, paraesthesia, peripheral neuropathy; anorexia; motion sickness; influenza-like symptoms; glycosuria, hyperglycaemia; electrolyte disturbance; arthralgia, eye irritation; amblyopia; tinnitus; rash, pruritus.
Pregnancy category ::
Drug Mode of Action ::
Palonosetron is a selective 5-HT3 antagonist that is used in the prevention of acute and delayed emesis in emetogenic cancer chemotherapy regimens.
Drug Interactions ::
May have additive effect on prolonging QT with drugs e.g. moxifloxacin, erythromycin, antipsychotics and TCAs.