Article Contents ::
Details About Generic Salt :: Pyridoxine
Main Medicine Class:: Vitamins Sub Medicine Class :: Vitamins , Minerals
| 20A. VITAMINS & MINERALS in 20. VITAMINS, MINERALS AND COMBINATIONS |
| PYRIDOXINE |
| WATER SOLUBLE VITAMIN | SUPPLEMENT |
| PK: A: Well absorbed M: Hepatic E: Urine |
|
Indications & Dose: DIETARY ALLOWANCE PO Adult Male: 1.7-2mg/day, Female: 1.4-1.6mg/day Child 1–3 yr: 0.9mg/day, 4–6 yr: 1.3mg/day, 7–10 yr: 1.6mg/day | DRUG INDUCED NEURITIS PO Adult Treatment: 100-200mg/day, Prophylaxis: 25-100mg/day Child Treatment: 10-50mg/day, Prophylaxis: 1-2mg/kg/day | SIDEROBLASTIC ANEMIA PO/IV/IM/SC General 400mg/day | TREATMENT AND PREVENTION OF PYRIDOXINE DEFICIENCY PO/IV/IM/SC General 150mg/day |
| Contra: Hypersensitivity
Precautions: Renal impairment, neonates ADR: Serious: seizures, peripheral neuropathy, neurotoxicity, Others: headache, acidosis, nausea, AST increases, allergic reaction DDI: Serious Nitrofurantoin causes paresthesias, Levodopa effect reduces/abolishes by drug, Phenytoin/Phenobarbital therapeutic efficacy reduces Monitor: Arterial blood gas, electrolytes, neurological exam, seizure activity |