Article Contents ::
Details About Generic Salt :: Reboxetine
Main Medicine Class:: Nervous System Sub Medicine Class :: Anti Depressants
| 1D. ANTI-DEPRESSANTS in 1. NERVOUS SYSTEM |
| REBOXETINE |
| SELECTIVE NOREPINEPHRINE INHIBITOR | ANTI-DEPRESSANT |
| PK: A: Well absorbed D: 32L M: Hepatic E: Urine |
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Indications & Dose: DEPRESSION PO Adult 4mg BID 3 wk, if no response increase dose to 10mg/day Elderly 2mg bid 3 wks, increase to 6mg/day if needed |
| Precautions: Urinary retention/BPH, renal/hepatic impairment, bipolar disorder, glaucoma, history of epilepsy, depression, CVD
ADR: Serious: allergic dermatitis, convulsions, orthostatic hypotension, hypokalemia, Others: urinary retention, erectile dysfunction, nausea, vomiting, anorexia, dry mouth, constipation, vertigo, tachycardia DDI: Serious MAOIs causes hypertensive crisis, Phenobarbital/Carbamazepine reduces drug level |
