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Details About Generic Salt :: Rizatriptan
Main Medicine Class:: #N/A Sub Medicine Class :: #N/A
| 1H. ANTI-MIGRAINE & ANTI- VERTIGO DRUGS in 1. NERVOUS SYSTEM |
| RIZATRIPTAN |
| 5-HT1 AGONIST | ANTI-MIGRAINE |
| PK: M: Hepatic E: Urine (82%); feces (12%) |
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Indications & Dose: MIGRAINE Acute PO Adult Initially 10mg if symptoms recur, another 10mg after 2h max 20mg/day (5mg in patients on propranolol max 10mg/day)Discontinue if ineffective for the first dose |
| Contra: Hypersensitivity, IHD/Prinzmetal’s angina, uncontrolled HTN, severe hepatic/renal impairment
Precautions: Mild-to-moderate hepatic/renal impairment ADR: Serious: TEN, coronary artery vasospasm, transient ischemia, MI, ventricular tachycardia/fibrillation, cardiac arrest, cerebral/subarachnoid hemorrhage, stroke, hypertensive crisis, peripheral vascular ischemia, colonic ischemia DDI: Serious Propranolol increases drug level, Moclobemide markedly inhibits drug metabolism Diet: Before food Monitor: Headache severity, ECG, HR, BP |