Article Contents ::
Details About Generic Salt :: Roxithromycin
Main Medicine Class:: Anti Infectives Sub Medicine Class :: Macrolides
| 13E. MACROLIDES in 13. ANTI-INFECTIVES |
| ROXITHROMYCIN |
| MACROLIDE ANTIBIOTIC | ANTI-INFECTIVE |
| PK: M: Hepatic E: Feces |
|
Indications & Dose: BACTERIAL INFECT PO Adult 300mg/day in single/divided doses Child 5-8mg/kg/day, max 150mg BIDCaused by susceptible organisms |
| Contra: Hypersensitivity
Precautions: hepatic impairment, history of arrhythmia, Predisposition to QT interval prolongation ADR: Serious: superinfection, hypersensitivity, SJS, TEN, cholestasis, hepatic dysfunction, tinnitus, agranulocytosis, pancreatitis, QT interval prolongation, arrhythmia, seizures, aggravate muscle weakness, Others: vertigo, thrombophlebitis, abdominal discomfort & cramp, nausea, vomiting, diarrhea, confusion, hallucinations DDI: Serious Midazolam effects modestly increased, Digoxin levels increases, Carbamazepine toxicity increases Diet: Before food |