Article Contents ::
Details About Generic Salt :: Tamsulosin
Main Medicine Class:: Genito Urinary System Sub Medicine Class :: Drugs For Prostate Disorders
| 10C. DRUGS FOR PROSTATE DISORDERS in 10. GENITO-URINARY SYSTEM |
| TAMSULOSIN |
| ALPHA-ADRENERGIC BLOCKER | DRUG FOR BPH |
| PK: A: >90% D: 16L (Vd) M: Hepatic E: Uirne & feces |
|
Indications & Dose: BENIGN PROSTATIC HYPERPLASIA Symptomatic therapy PO Adult MR: 400µg/day, may increase to 800µg/day after 2-4 wk if needed |
| Contra: Hypersensitivity, severe hepatic impairment
Precautions: Prostate cancer, priapism, orthostatic hypotension/syncope, intraoperative floppy iris syndrome, antihypertensives ADR: Serious: orthostatic hypotension, ejaculation abnormalities, rhinitis, blurred vision, pharyngitis, sinusitis, libido decreased, somnolence, floppy iris syndrome, Others: dizziness, headache, malaise, diarrhea, nausea, gum pain, weakness, toothache DDI: Serious Verapamil increases adverse effects of drug, Erythromycin/Cimetidine/Fluoxetine/Ketoconazole increases drug levels Diet: After food (30 min) Monitor: Vital signs |