Article Contents ::
Details About Generic Salt :: Teriparatide
Main Medicine Class:: Musculoskeletal Disorders , Pain Sub Medicine Class :: Drugs for Arthritis,Osteoporosis
12C. DRUGS FOR ARTHRITIS/OSTEOPOROSIS in 12. MUSCULOSKELETAL DISORDERS & PAIN |
TERIPARATIDE |
PARATHYROID HORMONE ANALOG | DRUG FOR OSTEOPOROSIS |
PK: A: Extensive D: 0.12L/kg (Vd) M: Hepatic E: Urine |
Indications & Dose: GLUCOCORTICOID-INDUCED OSTEOPOROSIS SC Adult 20µg OD into thigh/abdominal wall in patients at high risk of fracture | OSTEOPOROSIS IN POSTMENOPAUSAL WOMEN SC Adult 20µg OD into thigh/abdominal wall in patients at high risk of fracture | PRIMARY/HYPOGONADAL OSTEOPOROSIS SC Adult 20µg OD into thigh/abdominal wall in patients at high risk of fracture |
Contra: Hypersensitivity, severe renal impairment, metabolic bone disease including Paget’s disease & hyperparathyroidism, unexplained elevations of serum alkaline phosphatase, children with open epiphyses, pre-existing hypercalcemia, history of skeletal metastases
Precautions: Moderate renal impairment, should not drive/operate potentially hazardous machinery, CVD, hepatic impairment, active/recent urolithiasis ADR: Serious: Orthostatic hypotension, hyperuricemia, hypercalcemia, arthralgia, Others: dizziness, insomnia, anxiety, depression, vertigo, rash, nausea, gastritis, dyspepsia, vomiting, weakness, leg cramps, rhinitis, pharyngitis, dyspnea, pneumonia Monitor: Serum calcium, serum phosphorus, uric acid,BP, bone mineral density |