Article Contents ::
Details About Generic Salt :: Zopiclone
Main Medicine Class:: Nervous System Sub Medicine Class :: Sedatives , Hypnotics
| 1A. SEDATIVES & HYPNOTICS in 1. NERVOUS SYSTEM |
| ZOPICLONE |
| NON-BENZODIAZEPINE | HYPNOTIC |
| PK: A: Rapid D: Extensive M: Hepatic E: Urine (5%)& feces (16%) |
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Indications & Dose: INSOMNIA Short-term therapy PO Adult 7.5mg HS Elderly 3.75mg HS |
| Contra: Hypersensitivity to drug, myasthenia gravis, respiratory failure, severe sleep apnea syndrome, long-term therapy
Precautions: Elderly, muscle weakness, history of drug abuse, psychiatric illness, hepatic/renal impairment, depression, drug abuse/alcoholism, abrupt withdrawal ADR: Serious: Hypersensitivity reactions, sedation, depression, paradoxical excitation, respiratory depression, hypotension, disinhibition, jaundice, blood disorders, urinary retention/incontinence, visual disturbances, Others: GI disturbances, bitter or metallic taste, Headache, drowsiness, muscle weakness, ataxia, vertigo, confusion, slurred speech, libido, tremor DDI: Others Ketoconazole/Itraconazole increases drug level, Rifampicin reduces drug level Diet: After food (just before bedtime) Monitor: LFTs, excessive drowsiness (in elders) |