Details About Overdose or Poisoning Generic Salt :: Methylene Blue Methylene Blue Drug Pharmacology :: I. Pharmacology. A. Methyleneblue is a thiazine dye that increases the conversion of methemoglobinto hemoglobin. Methylene blue is reduced via methemoglobin reductaseand nicotinamide adenosine dinucleotide phosphate (NADPH) toleukomethylene blue, which in turn reduces methemoglobin.Glucose-6-phospate dehydrogenase is...
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Details About Overdose or Poisoning Generic Salt :: Methylene Blue Methylene Blue Drug Pharmacology :: I. Pharmacology. A. Methyleneblue is a thiazine dye that increases the conversion of methemoglobinto hemoglobin. Methylene blue is reduced via methemoglobin reductaseand nicotinamide adenosine dinucleotide phosphate (NADPH) toleukomethylene blue, which in turn reduces methemoglobin.Glucose-6-phospate dehydrogenase is...
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Details About Overdose or Poisoning Generic Salt :: Pentobarbital Pentobarbital Drug Pharmacology :: I. Pharmacology. Pentobarbitalis a short-acting barbiturate with anticonvulsant as well assedative-hypnotic properties. It is used as a third-line drug in thetreatment of status epilepticus. It also may reduce intracranialpressure in patients with cerebral edema by inducing vasoconstriction.After intravenous administration...
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Details About Overdose or Poisoning Generic Salt :: Phenytoin And Fosphenytoin Phenytoin and Fosphenytoin Drug Pharmacology :: I. Pharmacology.The neuronal membrane-stabilizing actions of phenytoin make this apopular drug for sustained control of acute and chronic seizuredisorders and a useful drug for certain cardiac arrhythmias. Because ofthe relatively slow onset of anticonvulsant action,...
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Details About Overdose or Poisoning Generic Salt :: BAL, Dimercaprol BAL (Dimercaprol) Drug Pharmacology :: I. Pharmacology. BAL(British anti-Lewisite, dimercaprol, 2,3-dimercaptopropanol) is adithiol chelating agent that is used in the treatment of poisoning bythe heavy metals arsenic, mercury, lead, and gold. Because the vicinalthiol groups are unstable in aqueous solution, the drug...
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Details About Overdose or Poisoning Generic Salt :: Naloxone And Nalmefene Naloxone and Nalmefene Drug Pharmacology :: I. Pharmacology. Naloxoneand nalmefene are pure opioid antagonists that competitively block mu,kappa, and delta opiate receptors within the CNS. They have no opioidagonist properties and can be given safely in large doses withoutproducing respiratory or...
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Details About Overdose or Poisoning Generic Salt :: Labetalol Labetalol Drug Pharmacology :: I. Pharmacology. Labetalolis a mixed alpha- and beta-adrenergic antagonist; after intravenousadministration, the nonselective beta-antagonist properties areapproximately sevenfold greater than the alpha-1 antagonist activity.Hemodynamic effects generally include decreases in heart rate, bloodpressure, and systemic vascular resistance. Atrioventricular conductionvelocity may be...
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Details About Overdose or Poisoning Generic Salt :: Nicotinamide, Niacinamide Nicotinamide (Niacinamide) Drug Pharmacology :: I. Pharmacology. Nicotinamide (niacinamide, vitamin B3),one of the B vitamins, is required for the functioning of the coenzymesnicotinamide adenine dinucleotide (NAD) and nicotinamide adeninedinucleotide phosphate (NADP). NAD and NADP are responsible for energytransfer reactions. Niacin deficiency, which...
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Details About Overdose or Poisoning Generic Salt :: Ipecac Syrup Ipecac Syrup Drug Pharmacology :: I. Pharmacology. Ipecacsyrup is a mixture of plant-derived alkaloids, principally emetine andcephaeline, that produce emesis by direct irritation of the stomach andstimulation of the central chemoreceptor trigger zone. Vomiting occursin 90% of these patients, usually within 20–30...
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Details About Overdose or Poisoning Generic Salt :: Acetylcysteine N Acetylcysteine, NAC Acetylcysteine (N-Acetylcysteine [NAC]) Drug Pharmacology :: I. Pharmacology. Acetylcysteine (N-acetylcysteine[NAC]) is a mucolytic agent that acts as a sulfhydryl group donor,substituting for the liver’s usual sulfhydryl donor, glutathione. Itrapidly binds (detoxifies) the highly reactive electrophilicintermediates of metabolism or it may...
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