Details About Generic Salt ::  Anastroz

Main Medicine Class::    

(an-ASS-troe-zole)

Arimidex

Tablets

1 mg

Class: Antineoplastic aromatase inhibitor

Drugs Class ::

 Action Significantly lowers serum estradiol concentrations by inhibiting aromatase, a mediary of endogenous estradiol production. There is no detectable effect on formation of adrenal corticosteroids or aldosterone.

Indications for Drugs ::

 Indications First-line treatment of postmenopausal women with hormone receptor positive or hormone receptor unknown locally advanced or metastatic breast cancer; second-line treatment of advanced breast cancer in postmenopausal women with disease progression following tamoxifen therapy; adjuvant treatment of postmenopausal women with hormone receptor positive early breast cancer.

Drug Dose ::

 Route/Dosage

First and Second-Line Therapy: ADULTS: PO 1 mg qd until tumor progression is evident.

Contraindication ::

 Contraindications None known.

Drug Precautions ::

 Precautions

Pregnancy: Category D. Lactation: Undetermined. Children: Safety and efficacy not established. Special Risk Patients: Severe hepatic impairment.

Drug Side Effects ::

 Adverse Reactions

CARDIOVASCULAR: Chest pain; hypertension; thromboembolic disease; thrombophlebitis; vasodilation. CNS: Anxiety; confusion; depression; dizziness; headache; hypertonia; insomnia; nervousness; somnolence. DERMATOLOGIC: Hair thinning; hot flushes; pruritus; rash GI: Abdominal pain; anorexia; constipation; diarrhea; nausea; vomiting. GU: Breast pain; leukorrhea; pelvic pain; urinary tract infection; vaginal dryness; vaginal hemorrhage. HEMATOLOGIC: Anemia; leukopenia. HEPATIC: Increated AST, gamma GT, and ALT. METABOLIC: Alkaline phosphatase increased. RESPIRATORY: Bronchitis; cough increased; dyspnea; pharyngitis; rhinitis; sinusitis. OTHER: Accidental injury; asthenia; pain; back pain; bone pain; depression; edema; fever; flu-like symptoms; increased appetite; infection; lethargy; malaise; peripheral edema; sweating; weight gain.

Drug Mode of Action ::  

 Action Significantly lowers serum estradiol concentrations by inhibiting aromatase, a mediary of endogenous estradiol production. There is no detectable effect on formation of adrenal corticosteroids or aldosterone.

Drug Interactions ::

 Interactions

Tamoxifen Plasma concentrations of anastrozole may be reduced.

Drug Assesment ::

 Precautions

Pregnancy: Category D. Lactation: Undetermined. Children: Safety and efficacy not established. Special Risk Patients: Severe hepatic impairment.

Drug Storage/Management ::

 Precautions

Pregnancy: Category D. Lactation: Undetermined. Children: Safety and efficacy not established. Special Risk Patients: Severe hepatic impairment.

Drug Notes ::

 Precautions

Pregnancy: Category D. Lactation: Undetermined. Children: Safety and efficacy not established. Special Risk Patients: Severe hepatic impairment.

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.