Details About Generic Salt ::  Atropin1

Main Medicine Class:: Anticholinergic,antispasmodic   

(AT-troe-peen SULL-fate/skoe-POLE-uh-meen HIGH-droe-BROE-mide/high-oh-SIGH-uh-meen SULL-fate/fee-no-BAR-bih-tahl)
Barbidonna, Barbidonna No. 2, Donnatal, Hyosophen, Spasmolin
Class: Anticholinergic/antispasmodic


Drugs Class ::

 Action Promotes peripheral anticholinergic/antispasmodic action (decreases GI motility); provides mild sedation.

Indications for Drugs ::

 Indications Possibly effective for treatment of irritable bowel syndrome and acute enterocolitis. Also may be useful as adjunctive therapy for duodenal ulcer.

Drug Dose ::


ADULTS: PO 1 to 2 tablets or capsules tid to qid; 1 extended-release tablet q 12 hr; 5 to 10 ml elixir tid to qid according to condition and severity of symptoms. CHILDREN: PO 0.5 to 5.0 ml elixir: q 4 hr to q 6 hr, according to body weight.

Contraindication ::

 Contraindications Glaucoma; obstructive uropathy; obstructive disease of the gastrointestinal tract; paralytic ileus; intestinal atony in elderly or debilitated patient; severe ulcerative colitis; toxic megacolon complicating ulcerative colitis; hepatic or renal disease; tachycardia; myocardial ischemia; unstable cardiovascular status in acute hemorrhage; myasthenia gravis; acute intermittent porphyrinuria.

Drug Precautions ::


Pregnancy: Category C. Lactation: If possible, do not use. Elderly patients: May react with agitation, drowsiness and other untoward manifestations even with small doses. Special risk patients: Used with caution in patients with neuropathy, hepatic or renal disease, hyperthyroidism, coronary artery disease, CHF, arrhythmias, hypertension or tachycardia. May complicate gastric ulcer treatment. Diarrhea: May be symptom of incomplete intestinal obstruction, especially in patients with ileostomy or colostomy and, therefore, may serve as contraindication. Heat prostration: Can occur in presence of high ambient temperature because of interference with normal sweating. Potentially hazardous tasks: May produce drowsiness, dizziness or blurred vision. Addiction potential: May be habit forming; when possible, not given to addiction-prone individual.


Drug Side Effects ::

 Adverse Reactions

CV: Palpitations; bradycardia; tachycardia; flushing. CNS: Headache; nervousness; drowsiness; weakness; dizziness; confusion; insomnia; fever (especially in children); mental confusion or excitement (especially in the elderly, even with small doses); CNS stimulation (restlessness, tremor), psychosis. DERM: Urticaria and other dermal manifestations of allergic reaction. EENT: Blurred vision; mydriasis; photophobia; cycloplegia; increased IOP; dilated pupils; nasal congestion; altered taste perception. GI: Xerostomia; nausea; vomiting; dysphagia; heartburn; constipation; bloated feeling; paralytic ileus. GU: Urinary hesitancy and retention; impotence. OTHER: Severe allergic reactions, including anaphylaxis; suppression of lactation; decreased sweating.

Drug Mode of Action ::  

 Action Promotes peripheral anticholinergic/antispasmodic action (decreases GI motility); provides mild sedation.

Drug Interactions ::


Anticoagulants: Anticoagulant effects may be decreased. Anticholinergic agents: Additive anticholingeric effects. Haloperidol: Worsened schizophrenic symptoms; decreased haloperidol concentrations. Phenothiazines: Decreased antipsychotic effects and increased anticholinergic effects may occur.

Drug Assesment ::


  • Obtain patient history, including drug history and any known allergies.
  • Monitor vital signs and LOC. Note any signs of hyperactivity or sedation.
  • Monitor I&O and bowel sounds. Notify physician of abdominal distention.
  • In patient with chronic lung disease, monitor lung sounds and effectiveness of cough.
  Dry mouth, thirst, vomiting, nausea, abdominal distention, CNS stimulation, delirium, drowsiness, restlessness, stupor, fever, seizures, hallucinations, convulsions, coma, “flat” EEG, circulatory failure, tachycardia, weak pulse, hypertension, hypotension, respiratory depression, palpitations, arrhythmias, urinary urgency, blurred vision, dilated pupils, photophobia, rash, dry and hot skin

Drug Storage/Management ::


  • Available for oral use only.
  • Store in a cool, dry place.

Drug Notes ::

 Patient/Family Education

  • Caution patient to have adequate oral intake.
  • Advise patient to include fiber in diet to prevent constipation.
  • Caution patient to limit exposure to high ambient temperatures.
  • Advise patient that dilated pupils may be experienced.
  • Warn patient that product may cause excitability or sedation. Remind patient not to drive or operate heavy machinery if sedation occurs.
  • Advise patient to notify physician if confusion, disorientation, ataxia, nausea, vomiting, diarrhea, abdominal distention, or elevated body temperature occurs. With ophthalmic preparations, also tell the patient to notify the doctor if eye pain is experienced.

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.


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