Article Contents ::

Details About Generic Salt ::  Botulinu

Main Medicine Class:: Botulinum Toxin   

Myobloc
Solution, injectable
5000 U/mL
Class: Botulinum Toxin

 Indications Reduction of severity of abnormal head position and neck pain in adult patients with cervical dystonia.

 Contraindications Standard considerations.

 Route/Dosage

ADULTS: In patients with known history of tolerance, 2500 to 5000 U divided among affected muscles. In patients without a history of tolerating botulinum toxin, administer a lower initial dose than in patients with known history of tolerance, adjusting subsequent doses based on individual response.

 Interactions

Aminoglycosides, Drugs Interfering with Neuromuscular Transmission: The effects of botulinum toxin may be potentiated.

 Lab Test Interferences None well documented.

 Adverse Reactions

CARDIOVASCULAR: Vasodilation. CNS: Dizziness; headache; migraine; anxiety; tremor; hyperesthesia; somnolence; confusion; vertigo. DERMATOLOGIC: Pruritus; ecchymosis. EENT: Dysphagia; rhinitis; glossitis; tooth disorder; amblyopia; otitis media; abnormal vision; taste perversion; tinnitus. GI: Dry mouth; dyspepsia; nausea; vomiting; GI disorder. GU: Urinary tract infection; cystitis; vaginal moniliasis. METABOLIC: Peripheral edema; edema; hypercholesterolemia. RESPIRATORY: Increased cough; dyspnea; lung disorder; pneumonia. OTHER: Neck pain and pain related to cervical dystonia; pain at injection site; infection; pain; flu syndrome; arthralgia; back pain; myasthenia; asthenia; accidental injury; allergic reaction; fever; chest pain; chills; hernia; malaise; abscess; cyst; neoplasm; viral infection.

 Precautions

Pregnancy: Category C. Lactation: Undetermined. Children: Safety and efficacy not established. Neuropathic Disorders: Use with caution in patients with neuropathic diseases because of increased risk of systemic effects including severe dysphagia and respiratory compromise.

PATIENT CARE CONSIDERATIONS


 Administration/Storage

NA

 Assessment/Interventions

OVERDOSAGE Systemic weakness, muscle paralysis

 Patient/Family Education

NA

 

Drugs Class ::

Myobloc
Solution, injectable
5000 U/mL
Class: Botulinum Toxin

Indications for Drugs ::

 Indications Reduction of severity of abnormal head position and neck pain in adult patients with cervical dystonia.

Drug Dose ::

 Route/Dosage

ADULTS: In patients with known history of tolerance, 2500 to 5000 U divided among affected muscles. In patients without a history of tolerating botulinum toxin, administer a lower initial dose than in patients with known history of tolerance, adjusting subsequent doses based on individual response.

Contraindication ::

 Contraindications Standard considerations.

Drug Precautions ::

 Precautions

Pregnancy: Category C. Lactation: Undetermined. Children: Safety and efficacy not established. Neuropathic Disorders: Use with caution in patients with neuropathic diseases because of increased risk of systemic effects including severe dysphagia and respiratory compromise.

PATIENT CARE CONSIDERATIONS


Drug Side Effects ::

 Adverse Reactions

CARDIOVASCULAR: Vasodilation. CNS: Dizziness; headache; migraine; anxiety; tremor; hyperesthesia; somnolence; confusion; vertigo. DERMATOLOGIC: Pruritus; ecchymosis. EENT: Dysphagia; rhinitis; glossitis; tooth disorder; amblyopia; otitis media; abnormal vision; taste perversion; tinnitus. GI: Dry mouth; dyspepsia; nausea; vomiting; GI disorder. GU: Urinary tract infection; cystitis; vaginal moniliasis. METABOLIC: Peripheral edema; edema; hypercholesterolemia. RESPIRATORY: Increased cough; dyspnea; lung disorder; pneumonia. OTHER: Neck pain and pain related to cervical dystonia; pain at injection site; infection; pain; flu syndrome; arthralgia; back pain; myasthenia; asthenia; accidental injury; allergic reaction; fever; chest pain; chills; hernia; malaise; abscess; cyst; neoplasm; viral infection.

Drug Mode of Action ::  

Myobloc
Solution, injectable
5000 U/mL
Class: Botulinum Toxin

Drug Interactions ::

 Interactions

Aminoglycosides, Drugs Interfering with Neuromuscular Transmission: The effects of botulinum toxin may be potentiated.

Drug Assesment ::

 Assessment/Interventions

OVERDOSAGE Systemic weakness, muscle paralysis

Drug Storage/Management ::

 Administration/Storage

NA

Drug Notes ::

 Patient/Family Education

NA

Disclaimer ::

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