Article Contents ::
- 1 Details About Generic Salt :: Cefditor
- 2 Main Medicine Class:: Antibiotic,Cephalosporin
- 3 (SEFF-dih-TORE-ehn pih-VOX-ill) Spectracef Class: Antibiotic/Cephalosporin Indications Treatment of mild to moderate infections of acute bacterial exacerbation of chronic bronchitis, pharyngitis/tonsillitis, and uncomplicated skin and skin-structure infections due to susceptible strains of specific microorganisms. Contraindications Hypersensitivity to cephalosporins or milk protein; carnitine deficiency or inborn errors of metabolism that result in clinically important carnitine deficiency. Route/Dosage Acute Bacterial Exacerbation of Chronic Bronchitis ADULTS and CHILDREN (³ 12 yr): PO 400 mg bid for 10 days. Pharyngitis/Tonsillitis and Uncomplicated Skin and Skin-Structure Infections ADULTS and CHILDREN (³ 12 yr): PO 200 mg bid for 10 days. Renal Insufficiency ADULTS and CHILDREN (³ 12 yr): PO Mild renal impairment (Ccr 50 to 80 mL/min/1.73 m2) no dosage adjustment is necessary; moderate renal impairment (Ccr 30 to 49 mL/min/1.73 m2) < 200 mg bid; severe renal impairment (Ccr < 30 mL/min/1.73 m2) 200 mg daily; dose in end-stage renal disease not determined. Interactions Antacids, H2 -receptor antagonists (eg, famotidine): May decrease cefditoren plasma levels, possibly reducing the efficacy. Probenecid: May increase plasma levels and the duration of activity of cefditoren. Lab Test Interferences May cause false-positive direct Coombs test; may cause false-positive urine glucose test results with Benedict or Fehling solution or Clinitest tablets but not with enzyme-based tests (eg, Clinistix, Tes-Tape); may cause false-negative test in the ferricyanide test for blood glucose but not the glucose oxidase or hexokinase methods of determination. Adverse Reactions CNS: Headache; reversible hyperactivity; seizures. DERMATOLOGIC: Stevens-Johnson syndrome; erythema multiforme; toxic epidermal necrolysis. GI: Diarrhea; nausea; abdominal pain; dyspepsia; vomiting; pseudomembranous colitis; colitis. GU: Vaginal moniliasis; hematuria; increased urine WBC; renal dysfunction; toxic nephropathy. HEMATOLOGIC: Decreased hematocrit; aplastic anemia; hemolytic anemia; hemorrhage; pancytopenia; neutropenia; agranulocytosis. HEPATIC: Hepatic dysfunction (eg, cholestasis). METABOLIC: Increased glucose. OTHER: Allergic reactions; anaphylaxis; drug fever; hypertonia; superinfection; serum sickness-like reaction. Precautions Pregnancy: Category B. Lactation: Undetermined. Children: Safety and efficacy not determined in children < 12 yr. Elderly: Because elderly patients are more likely to have decreased renal function, select dose with caution. Hypersensitivity: Reactions range from mild to life-threatening. Administer drug with caution to penicillin-sensitive patients because of possible cross-reactivity. Pseudomembranous colitis: Consider pseudomembranous colitis as a possibility in patients who develop diarrhea. Renal impairment: Dosage adjustment is necessary. Superinfection: Drug may cause bacterial or fungal overgrowth of nonsusceptible microorganisms. PATIENT CARE CONSIDERATIONS Administration/Storage Medication is usually administered twice daily. Administer each dose with food to increase absorption. Administer reduced dose to patient with renal impairment. Store tablets at controlled room temperature (59° to 86°F). Protect from light and moisture. Assessment/Interventions Obtain patient history, including drug history and any known allergies. Note history of allergy to penicillins, cephalosporins or milk protein, renal impairment, severe hepatic impairment, carnitine deficiency, or inborn errors of metabolism that may result in carnitine deficiency. Review results of culture and sensitivity testing as available. Monitor for signs of infection, especially fever, and for positive response to antibiotic therapy. Monitor patient for signs of anaphylaxis or severe allergic reaction. Discontinue therapy and immediately notify health care provider if noted. Be prepared to treat appropriately. Monitor patient for GI side effects. Report to health care provider if noted and significant. OVERDOSAGE: SIGNS & SYMPTOMS Nausea, vomiting, epigastric distress, diarrhea, convulsions Patient/Family Education Explain name, dose, action, and potential side effects of drug. Review dosing schedule and prescribed length of therapy with patient. Instruct patient to take each dose with food to enhance absorption. Instruct patient not to take antacids or other acid-suppressive therapy (eg, H2-receptor antagonists, proton pump inhibitors) concomitantly with this medication. Remind patient, family, or caregiver to complete entire course of therapy, even if symptoms of infection have disappeared. Advise patient, family, or caregiver to discontinue therapy and contact the health care provider immediately if skin rash, hives, itching, or shortness of breath occurs. Advise patient, family, or caregiver to report the following signs of superinfection to health care provider: black “furry” tongue, white patches in mouth, foul-smelling stools, vaginal itching or discharge. Warn patient, family, or caregiver that diarrhea containing blood or pus may be a sign of a serious disorder and to seek medical care if noted and not to treat at home. Instruct patient not to take any prescription or otc medications or dietary supplements unless advised to do so by the health care provider. Advise patient, family, or caregiver that follow-up examinations and lab tests may be required to monitor therapy and to be sure and keep appointments. –>
- 4 Drugs Class ::
- 5 Disclaimer ::
- 6 The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.
Details About Generic Salt :: Cefditor
Main Medicine Class:: Antibiotic,Cephalosporin
(SEFF-dih-TORE-ehn pih-VOX-ill)
Spectracef
Class: Antibiotic/Cephalosporin
Indications Treatment of mild to moderate infections of acute bacterial exacerbation of chronic bronchitis, pharyngitis/tonsillitis, and uncomplicated skin and skin-structure infections due to susceptible strains of specific microorganisms.
Contraindications Hypersensitivity to cephalosporins or milk protein; carnitine deficiency or inborn errors of metabolism that result in clinically important carnitine deficiency.
Route/Dosage
Acute Bacterial Exacerbation of Chronic Bronchitis
ADULTS and CHILDREN (³ 12 yr): PO 400 mg bid for 10 days.
Pharyngitis/Tonsillitis and Uncomplicated Skin and Skin-Structure Infections
ADULTS and CHILDREN (³ 12 yr): PO 200 mg bid for 10 days.
Renal Insufficiency
ADULTS and CHILDREN (³ 12 yr): PO Mild renal impairment (Ccr 50 to 80 mL/min/1.73 m2) no dosage adjustment is necessary; moderate renal impairment (Ccr 30 to 49 mL/min/1.73 m2) < 200 mg bid; severe renal impairment (Ccr < 30 mL/min/1.73 m2) 200 mg daily; dose in end-stage renal disease not determined.
Interactions
Antacids, H2 -receptor antagonists (eg, famotidine): May decrease cefditoren plasma levels, possibly reducing the efficacy. Probenecid: May increase plasma levels and the duration of activity of cefditoren.
Lab Test Interferences May cause false-positive direct Coombs test; may cause false-positive urine glucose test results with Benedict or Fehling solution or Clinitest tablets but not with enzyme-based tests (eg, Clinistix, Tes-Tape); may cause false-negative test in the ferricyanide test for blood glucose but not the glucose oxidase or hexokinase methods of determination.
Adverse Reactions
CNS: Headache; reversible hyperactivity; seizures. DERMATOLOGIC: Stevens-Johnson syndrome; erythema multiforme; toxic epidermal necrolysis. GI: Diarrhea; nausea; abdominal pain; dyspepsia; vomiting; pseudomembranous colitis; colitis. GU: Vaginal moniliasis; hematuria; increased urine WBC; renal dysfunction; toxic nephropathy. HEMATOLOGIC: Decreased hematocrit; aplastic anemia; hemolytic anemia; hemorrhage; pancytopenia; neutropenia; agranulocytosis. HEPATIC: Hepatic dysfunction (eg, cholestasis). METABOLIC: Increased glucose. OTHER: Allergic reactions; anaphylaxis; drug fever; hypertonia; superinfection; serum sickness-like reaction.
Precautions
Pregnancy: Category B. Lactation: Undetermined. Children: Safety and efficacy not determined in children < 12 yr. Elderly: Because elderly patients are more likely to have decreased renal function, select dose with caution. Hypersensitivity: Reactions range from mild to life-threatening. Administer drug with caution to penicillin-sensitive patients because of possible cross-reactivity. Pseudomembranous colitis: Consider pseudomembranous colitis as a possibility in patients who develop diarrhea. Renal impairment: Dosage adjustment is necessary. Superinfection: Drug may cause bacterial or fungal overgrowth of nonsusceptible microorganisms.
PATIENT CARE CONSIDERATIONS
Administration/Storage
- Medication is usually administered twice daily.
- Administer each dose with food to increase absorption.
- Administer reduced dose to patient with renal impairment.
- Store tablets at controlled room temperature (59° to 86°F). Protect from light and moisture.
Assessment/Interventions
- Obtain patient history, including drug history and any known allergies. Note history of allergy to penicillins, cephalosporins or milk protein, renal impairment, severe hepatic impairment, carnitine deficiency, or inborn errors of metabolism that may result in carnitine deficiency.
- Review results of culture and sensitivity testing as available.
- Monitor for signs of infection, especially fever, and for positive response to antibiotic therapy.
- Monitor patient for signs of anaphylaxis or severe allergic reaction. Discontinue therapy and immediately notify health care provider if noted. Be prepared to treat appropriately.
- Monitor patient for GI side effects. Report to health care provider if noted and significant.
OVERDOSAGE: SIGNS & SYMPTOMS
Nausea, vomiting, epigastric distress, diarrhea, convulsions
Patient/Family Education
- Explain name, dose, action, and potential side effects of drug.
- Review dosing schedule and prescribed length of therapy with patient.
- Instruct patient to take each dose with food to enhance absorption.
- Instruct patient not to take antacids or other acid-suppressive therapy (eg, H2-receptor antagonists, proton pump inhibitors) concomitantly with this medication.
- Remind patient, family, or caregiver to complete entire course of therapy, even if symptoms of infection have disappeared.
- Advise patient, family, or caregiver to discontinue therapy and contact the health care provider immediately if skin rash, hives, itching, or shortness of breath occurs.
- Advise patient, family, or caregiver to report the following signs of superinfection to health care provider: black “furry” tongue, white patches in mouth, foul-smelling stools, vaginal itching or discharge.
- Warn patient, family, or caregiver that diarrhea containing blood or pus may be a sign of a serious disorder and to seek medical care if noted and not to treat at home.
- Instruct patient not to take any prescription or otc medications or dietary supplements unless advised to do so by the health care provider.
- Advise patient, family, or caregiver that follow-up examinations and lab tests may be required to monitor therapy and to be sure and keep appointments.
–>
Indications Treatment of mild to moderate infections of acute bacterial exacerbation of chronic bronchitis, pharyngitis/tonsillitis, and uncomplicated skin and skin-structure infections due to susceptible strains of specific microorganisms. Contraindications Hypersensitivity to cephalosporins or milk protein; carnitine deficiency or inborn errors of metabolism that result in clinically important carnitine deficiency. Route/Dosage Interactions Lab Test Interferences May cause false-positive direct Coombs test; may cause false-positive urine glucose test results with Benedict or Fehling solution or Clinitest tablets but not with enzyme-based tests (eg, Clinistix, Tes-Tape); may cause false-negative test in the ferricyanide test for blood glucose but not the glucose oxidase or hexokinase methods of determination. Adverse Reactions PrecautionsPATIENT CARE CONSIDERATIONS
Administration/Storage Assessment/Interventions| OVERDOSAGE: SIGNS & SYMPTOMS | |
| Nausea, vomiting, epigastric distress, diarrhea, convulsions | |
Patient/Family Education
Drugs Class ::
| (SEFF-dih-TORE-ehn pih-VOX-ill) |
| Spectracef |
| Class: Antibiotic/Cephalosporin |
Indications for Drugs ::
Indications Treatment of mild to moderate infections of acute bacterial exacerbation of chronic bronchitis, pharyngitis/tonsillitis, and uncomplicated skin and skin-structure infections due to susceptible strains of specific microorganisms.
Drug Dose ::
Route/Dosage
Acute Bacterial Exacerbation of Chronic Bronchitis
ADULTS and CHILDREN (³ 12 yr): PO 400 mg bid for 10 days.
Pharyngitis/Tonsillitis and Uncomplicated Skin and Skin-Structure Infections
ADULTS and CHILDREN (³ 12 yr): PO 200 mg bid for 10 days.
Renal Insufficiency
ADULTS and CHILDREN (³ 12 yr): PO Mild renal impairment (Ccr 50 to 80 mL/min/1.73 m2) no dosage adjustment is necessary; moderate renal impairment (Ccr 30 to 49 mL/min/1.73 m2) < 200 mg bid; severe renal impairment (Ccr < 30 mL/min/1.73 m2) 200 mg daily; dose in end-stage renal disease not determined.
Contraindication ::
Contraindications Hypersensitivity to cephalosporins or milk protein; carnitine deficiency or inborn errors of metabolism that result in clinically important carnitine deficiency.
Drug Precautions ::
Precautions
Pregnancy: Category B. Lactation: Undetermined. Children: Safety and efficacy not determined in children < 12 yr. Elderly: Because elderly patients are more likely to have decreased renal function, select dose with caution. Hypersensitivity: Reactions range from mild to life-threatening. Administer drug with caution to penicillin-sensitive patients because of possible cross-reactivity. Pseudomembranous colitis: Consider pseudomembranous colitis as a possibility in patients who develop diarrhea. Renal impairment: Dosage adjustment is necessary. Superinfection: Drug may cause bacterial or fungal overgrowth of nonsusceptible microorganisms.
|
PATIENT CARE CONSIDERATIONS |
|
Drug Side Effects ::
Adverse Reactions
CNS: Headache; reversible hyperactivity; seizures. DERMATOLOGIC: Stevens-Johnson syndrome; erythema multiforme; toxic epidermal necrolysis. GI: Diarrhea; nausea; abdominal pain; dyspepsia; vomiting; pseudomembranous colitis; colitis. GU: Vaginal moniliasis; hematuria; increased urine WBC; renal dysfunction; toxic nephropathy. HEMATOLOGIC: Decreased hematocrit; aplastic anemia; hemolytic anemia; hemorrhage; pancytopenia; neutropenia; agranulocytosis. HEPATIC: Hepatic dysfunction (eg, cholestasis). METABOLIC: Increased glucose. OTHER: Allergic reactions; anaphylaxis; drug fever; hypertonia; superinfection; serum sickness-like reaction.
Drug Mode of Action ::
| (SEFF-dih-TORE-ehn pih-VOX-ill) |
| Spectracef |
| Class: Antibiotic/Cephalosporin |
Drug Interactions ::
Interactions
Antacids, H2 -receptor antagonists (eg, famotidine): May decrease cefditoren plasma levels, possibly reducing the efficacy. Probenecid: May increase plasma levels and the duration of activity of cefditoren.
Drug Assesment ::
Assessment/Interventions
- Obtain patient history, including drug history and any known allergies. Note history of allergy to penicillins, cephalosporins or milk protein, renal impairment, severe hepatic impairment, carnitine deficiency, or inborn errors of metabolism that may result in carnitine deficiency.
- Review results of culture and sensitivity testing as available.
- Monitor for signs of infection, especially fever, and for positive response to antibiotic therapy.
- Monitor patient for signs of anaphylaxis or severe allergic reaction. Discontinue therapy and immediately notify health care provider if noted. Be prepared to treat appropriately.
- Monitor patient for GI side effects. Report to health care provider if noted and significant.
|
||||
Drug Storage/Management ::
Administration/Storage
- Medication is usually administered twice daily.
- Administer each dose with food to increase absorption.
- Administer reduced dose to patient with renal impairment.
- Store tablets at controlled room temperature (59° to 86°F). Protect from light and moisture.
Drug Notes ::
Patient/Family Education
- Explain name, dose, action, and potential side effects of drug.
- Review dosing schedule and prescribed length of therapy with patient.
- Instruct patient to take each dose with food to enhance absorption.
- Instruct patient not to take antacids or other acid-suppressive therapy (eg, H2-receptor antagonists, proton pump inhibitors) concomitantly with this medication.
- Remind patient, family, or caregiver to complete entire course of therapy, even if symptoms of infection have disappeared.
- Advise patient, family, or caregiver to discontinue therapy and contact the health care provider immediately if skin rash, hives, itching, or shortness of breath occurs.
- Advise patient, family, or caregiver to report the following signs of superinfection to health care provider: black “furry” tongue, white patches in mouth, foul-smelling stools, vaginal itching or discharge.
- Warn patient, family, or caregiver that diarrhea containing blood or pus may be a sign of a serious disorder and to seek medical care if noted and not to treat at home.
- Instruct patient not to take any prescription or otc medications or dietary supplements unless advised to do so by the health care provider.
- Advise patient, family, or caregiver that follow-up examinations and lab tests may be required to monitor therapy and to be sure and keep appointments.
–>
