Details About Generic Salt ::  Penicil1

Main Medicine Class:: Antibiotic, Penicillin   

(pen-ih-SILL-in V)
Tablets: 250 mg
Tablets: 500 mg
Powder for oral solution: 125 mg/5 mL
Powder for oral solution: 250 mg/5 mL
Pen-Vee K
Tablets: 250 mg
Tablets: 500 mg
Powder for oral solution: 125 mg/5 mL
Powder for oral solution: 250 mg/5 mL
Penicillin VK
Tablets: 250 mg
Tablets: 500 mg
Powder for oral solution: 125 mg/5 mL
Powder for oral solution: 250 mg/5 mL
Tablets: 250 mg
Tablets: 500 mg
Powder for oral solution: 125 mg/5 mL
Veetids ‘250’
Powder for oral solution: 250 mg/5 mL
V-cillin K
Class: Antibiotic, Penicillin


Drugs Class ::

 Action Inhibits mucopeptide synthesis of bacterial cell wall.

Indications for Drugs ::

 Indications Treatment of upper respiratory tract infections; treatment of pneumococcal, streptococci, and staphylococcal infections and fusospirochetosis (Vincent’s infection) of oropharynx caused by susceptible microorganisms.

Prophylactic treatment of sickle cell anemia in children; treatment of anaerobic infections; treatment of Lyme disease (Borrelia burgdorferi).

Drug Dose ::


Adults and Children over 12 yr: PO 125 to 500 mg qid.

Contraindication ::

 Contraindications Hypersensitivity to penicillins. Do not treat severe pneumonia, empyema, bacteremia, pericarditis, meningitis, and purulent or septic arthritis with oral penicillin V during acute stage.

Drug Precautions ::


Pregnancy: Category B. Lactation: Small amount excreted in breast milk. May cause diarrhea, candidiasis, or allergic response in nursing infant. Hypersensitivity: Reactions range from mild to life threatening. Administer drug with caution to cephalosporin-sensitive patients because of possible crossreactivity. Pseudomembranous colitis: May occur because of overgrowth of clostridia. Renal impairment: Use drug with caution; dosage adjustment may be necessary. Streptococcal infections: Therapy must be minimum of 10 days. Superinfection: May result in bacterial or fungal overgrowth of nonsusceptible organisms.


Drug Side Effects ::

 Adverse Reactions

CNS: Dizziness; fatigue; insomnia; reversible hyperactivity; neurotoxicity (eg, lethargy, neuromuscular irritability, hallucinations, convulsions, seizures). EENT: Itchy eyes; furry tongue; black “hairy” tongue; stomatitis; sore mouth or tongue. GI: Glossitis; gastritis; dry mouth; nausea; vomiting; abdominal pain or cramp; epigastric distress; diarrhea or bloody diarrhea; rectal bleeding; flatulence; enterocolitis; pseudomembranous colitis. GU: Interstitial nephritis (eg, oliguria, proteinuria, hematuria, hyaline casts, pyuria); nephropathy; increased BUN and creatinine. HEMATOLOGIC: Decreased hemoglobin, hematocrit, RBC, WBC, neutrophils, lymphocytes, platelets; increased lymphocytes, monocytes, basophils, eosinophils, and platelets. METABOLIC: Elevated serum alkaline phosphatase; hypernatremia; hypokalemia; albumin, total proteins and uric acid. OTHER: Hypersensitivity reactions (eg, urticaria, angioneurotic edema, laryngospasm, laryngeal edema, bronchospasm, hypotension, vascular collapse, death, maculopapular to exfoliative dermatitis, vesicular eruptions, erythema multiforme, serum sickness, skin rashes, prostration); vaginitis; hyperthermia.

Drug Mode of Action ::  

 Action Inhibits mucopeptide synthesis of bacterial cell wall.

Drug Interactions ::


Beta-blockers: May potentiate anaphylactic reactions of penicillin. Contraceptives, oral: May reduce efficacy of oral contraceptives. Erythromycin: May cause synergism or antagonism to develop. Tetracyclines: May impair bactericidal effects of penicillin V.

Drug Assesment ::


  • Obtain patient history, including drug history and any known allergies.
  • Assess patient for infection at beginning and throughout therapy (eg, fever, WBC, appearance of wound).
  • Obtain specimens for culture and sensitivity before beginning therapy.
  • Observe for anaphylaxis. People with no history of hypersensitivity may develop allergic response.
  • Assess for signs of superinfection (eg, bacterial or fungal overgrowth of nonsusceptible organisms).
  • Monitor renal function, especially in patients with renal impairment.
  • If patient develops rash, pruritus, laryngeal edema, wheezing or evidence of hemolytic anemia (positive Coomb’s test), or other signs of an allergic reaction, discontinue drug and notify health care provider.
  • If sudden elevation in temperature develops, notify health care provider; it may be drug fever.
  • Discontinue use of penicillin V if signs of hemolytic anemia develop (positive Coomb’s test).
  Neuromuscular hyperexcitability, agitation, confusion, asterixis, hallucinations, stupor, coma, multifocal myoclonus, encephalopathy, hyperkalemia

Drug Storage/Management ::


  • Administer without regard to food.
  • Administer at regular intervals around the clock.
  • Reconstituted oral suspension is stable for 14 days when refrigerated. Shake well before using.

Drug Notes ::

 Patient/Family Education

  • Instruct patient to complete entire course of therapy even if feeling better.
  • Advise patient to use calibrated measuring device for liquid preparation.
  • Instruct penicillin allergic patient to carry Medi-Alert necklace or bracelet.
  • Advise patient to use nonhormonal form of contraceptive during penicillin V therapy.
  • Inform patient of the signs of hypersensitivity (eg, skin rash, itching, hives, shortness of breath, wheezing) and other side effects, such as black tongue, sore throat, nausea, vomiting, severe diarrhea, fever, swollen joints. Instruct patient to notify health care provider if these symptoms occur.
  • Instruct patient to notify health care provider if there is no improvement in symptoms of infection.
  • Instruct patient to notify health care provider of signs of superinfection (eg, vaginitis, black “hairy” tongue).

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.


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